Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL925449 | 0.77 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL3712396 | 0.77 | TAAR1 (0.48) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL5610136 | 0.77 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL9271997 | 0.76 | TAAR1 (0.58) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL1396353 | 0.74 | TAAR1 (0.56) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL6438136 | 0.74 | SMN1; SMN2 (0.55) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL9070292 | 0.73 | SLC6A2 (0.54) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL4982665 | 0.73 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| Hydrochloric Acid SCHEMBL6509443 | 0.72 | TAAR1 (0.54) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL5885752 | 0.72 | TAAR1 (0.58) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190248956-A1 | POLY(L-LYSINE ISOLPHTHALAMIDE) (PLP) POLYMERS WITH HYDROPHOBIC PENDANT CHAINS | IMPERIAL INNOVATIONS LIMITED (GB) | 2019-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190248956-A1 | POLY(L-LYSINE ISOLPHTHALAMIDE) (PLP) POLYMERS WITH HYDROPHOBIC PENDANT CHAINS | PLP2, LNPEP, PLPBP | CYP1A2 4861/4885CYP2C9 4866/4885CYP2C19 4852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.