SCHEMBL925449

SCHEMBL925449

NCC(O)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.52
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
FDPS P14324 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.48
HIF1A Q16665 1/20 0.48
TAAR1 Q96RJ0 2/20 0.48
SLC6A2 P23975 1/20 0.48
LOXL2 Q9Y4K0 2/20 0.46
CYP2A6 P11509 1/20 0.42
HTR2A P28223 1/20 0.42
KIF11 P52732 2/20 0.41
CYP2D6 P10635 3/20 0.41
CYP3A4 P08684 2/20 0.41
PRMT1 Q99873 1/20 0.41
TSHR P16473 2/20 0.40
KCNA5 P22460 1/20 0.40
LMNA P02545 1/20 0.40
RECQL P46063 1/20 0.40
TRPA1 O75762 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27845326 0.90 SMN1; SMN2 (0.50) CYP1A2CYP2C9CYP2C19FDPSSMN1; SMN2
SCHEMBL28135896 0.87 TAAR1 (0.47) CYP1A2CYP2C9CYP2C19FDPSSMN1; SMN2
SCHEMBL28607388 0.85 CYP1A2 (0.61) CYP1A2CYP2C9CYP2C19FDPSSMN1; SMN2
SCHEMBL11106147 0.84 TAAR1 (0.44) CYP1A2CYP2C9CYP2C19FDPSSMN1; SMN2
Ammonia Solution, Strong SCHEMBL4608399 0.82 CYP1A2 (0.58) CYP1A2CYP2C9CYP2C19FDPSSMN1; SMN2
SCHEMBL11106957 0.81 TAAR1 (0.41) CYP1A2CYP2C9CYP2C19FDPSSMN1; SMN2
SCHEMBL9271997 0.79 TAAR1 (0.58) CYP1A2CYP2C9CYP2C19FDPSSMN1; SMN2
SCHEMBL3273807 0.78 CYP1A2 (0.54) CYP1A2CYP2C9CYP2C19FDPSSMN1; SMN2
SCHEMBL7276106 0.77 HTR2A (0.50) CYP1A2CYP2C19FDPSSMN1; SMN2TAAR1
SCHEMBL21243974 0.77 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19FDPSSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115710464-A Silicon oxide dielectric layer chemical mechanical polishing solution with low surface roughness 博力思(天津)电子科技有限公司 2023-02-24 CN claimed
CN-115710464-A Silicon oxide dielectric layer chemical mechanical polishing solution with low surface roughness 博力思(天津)电子科技有限公司 2023-02-24 CN disclosed
CN-109096128-B Preparation method of aminopolyethylene glycol propionic acid 江苏金斯瑞生物科技有限公司 2021-03-09 CN disclosed
EP-3006437-B1 (+)-5-(3,4-DIFLUOROPHENYL)-5-[(3-METHYL-2-OXOPYRIDIN-1(2H)-YL)METHYL]IMIDAZOLIDINE-2,4-DIONE AND DRUG CONTAINING SAME KAKEN PHARMA CO LTD (JP) 2020-08-05 EP disclosed
EP-2617812-B1 COMPOSITION FOR MAINTAINING PLATELET FUNCTION UNIV TOKYO (JP) 2019-03-20 EP disclosed
US-10000476-B2 Pyridone derivative, pharmaceutical containing the same and methods of use thereof KAKEN PHARMACEUTICAL CO., LTD. (JP) 2018-06-19 US disclosed
EP-3009426-B1 4-ALKYNYL IMIDAZOLE DERIVATIVE AND MEDICINE COMPRISING SAME AS ACTIVE INGREDIENT KAKEN PHARMA CO LTD (JP) 2018-05-02 EP disclosed
EP-2789607-B1 PYRIDONE DERIVATIVE AND MEDICINE CONTAINING SAME KAKEN PHARMA CO LTD (JP) 2018-02-07 EP disclosed
US-9855257-B2 4-alkynyl imidazole derivative and medicine comprising same as active ingredient KAKEN PHARMACEUTICAL CO., LTD. (JP) 2018-01-02 US disclosed
US-20170128431-A1 4-ALKYNYL IMIDAZOLE DERIVATIVE AND MEDICINE COMPRISING SAME AS ACTIVE INGREDIENT KAKEN PHARMACEUTICAL CO., LTD. (JP) 2017-05-11 US disclosed
CN-101742909-A Have purposes and weed killer herbicide and the algaecide composition of the compound of single galactosyl DG synthase inhibitory activity as weed killer herbicide or algicide CENTRE NAT RECH SCIENT 2010-06-16 CN disclosed
EP-2094079-A1 COMPOSITION FOR REPELLING AND DETERRING VERMIN Novartis Ag (CH) 2009-09-02 EP disclosed
CN-101460468-A 2-pyrazinecarboxamide derivatives HOFFMANN LA ROCHE (CH) 2009-06-17 CN disclosed
US-7511144-B2 Reverse hydroxamic acid derivatives KAKEN PHARMACEUTICAL CO., LTD. (JP) 2009-03-31 US disclosed
EP-1431285-B1 REVERSE HYDROXAMIC ACID DERIVATIVES KAKEN PHARMA CO LTD (JP) 2009-01-07 EP disclosed
WO-2008062006-A1 COMPOSITION FOR REPELLING AND DETERRING VERMIN NOVARTIS AG (CH) 2008-05-29 WO disclosed
US-20040242928-A1 Tumor necrosis factor converting enzyme inhibitor; antiarthritic agents; lupus; Crohn's disease; multiple sclerosis; antidiabetic agents; infections;; asthma; skin disorders; anemia STUDOR S.A. (LU) 2004-12-02 US disclosed
EP-1431285-A1 REVERSE HYDROXAMIC ACID DERIVATIVES Kaken Pharmaceutical Co., Ltd. (JP) 2004-06-23 EP disclosed
US-4353787-A COATINGS, ADHESIVES, CASTINGS, REINFORCED COMPOSITES SCOTT BADER COMPANY LIMITED (GB) 1982-10-12 US disclosed
US-4226969-A AMINE HARDENER, AMINOALCOHOL ALLIED PRODUCTS CORPORATION (US) 1980-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10000476-B2 Pyridone derivative, pharmaceutical containing the same and methods of use thereof PNPO, PDXK, PLPBP CYP1A2 20/4885CYP2C9 34/4885CYP2C19 6/4885
US-20170128431-A1 4-ALKYNYL IMIDAZOLE DERIVATIVE AND MEDICINE COMPRISING SAME AS ACTIVE INGREDIENT PTGER4, IL4, PTGER1 CYP1A2 469/4885CYP2C9 707/4885CYP2C19 209/4885
US-20040242928-A1 Tumor necrosis factor converting enzyme inhibitor; antiarthritic agents; lupus; Crohn's disease; multiple sclerosis; antidiabetic agents; infections;; asthma; skin disorders; anemia TNF, RNASE1, IFNAR1 CYP1A2 1130/4885CYP2C9 3181/4885CYP2C19 2346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.