Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8152451 | 0.80 | HTR1A (0.42) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL12582119 | 0.78 | MAPT (0.67) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL4702062 | 0.75 | ADRA2C (0.54) | ALDH1A1MAPTLMNAKDM4ETP53 | |
| SCHEMBL6969236 | 0.74 | RAD52 (0.57) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL10367148 | 0.74 | LMNA (0.49) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL8334018 | 0.74 | MAPT (0.49) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL8159508 | 0.74 | LMNA (0.53) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL7839832 | 0.74 | MAPT (0.49) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL7331424 | 0.74 | MAPT (0.49) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL23732123 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNARAD52RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019148575-A1 | NOVEL USE OF PYRIDINE COMPOUND | 中国科学院广州生物医药与健康研究院 | 2019-08-08 | — | — | WO | disclosed |