Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955718 | 1.00 | CYP2A6 (0.57) | CYP2A6CYP1A2ALDH1A1TDP1KDM4E | |
| SCHEMBL29955696 | 0.85 | CYP1A2 (0.57) | CYP2A6CYP1A2ALDH1A1TDP1KDM4E | |
| SCHEMBL9437612 | 0.85 | CYP1A2 (0.57) | CYP2A6CYP1A2ALDH1A1TDP1KDM4E | |
| SCHEMBL21244243 | 0.81 | CYP1A2 (0.57) | CYP2A6CYP1A2ALDH1A1TDP1KDM4E | |
| SCHEMBL9883875 | 0.78 | KIF11 (0.42) | CYP2A6ALDH1A1TDP1KDM4EMEN1 | |
| SCHEMBL9485988 | 0.78 | CYP2A6 (0.49) | CYP2A6CYP1A2ALDH1A1TDP1MEN1 | |
| SCHEMBL31661013 | 0.78 | CYP2A6 (0.49) | CYP2A6CYP1A2ALDH1A1TDP1MEN1 | |
| SCHEMBL813387 | 0.78 | ERN1 (0.47) | CYP2A6CYP1A2ALDH1A1TDP1KDM4E | |
| SCHEMBL1817898 | 0.77 | MEN1 (0.48) | CYP2A6CYP1A2ALDH1A1TDP1KDM4E | |
| SCHEMBL11042152 | 0.77 | ALDH1A1 (0.45) | CYP2A6CYP1A2ALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701608-B2 | Process for the synthesis of 7-methoxy-naphthalene-1-carbaldehyde and application in the synthesis of agomelatine | LES LABORATORIES SERVIER (FR) | 2017-07-11 | — | — | US | disclosed |
| US-20160304429-A1 | PROCESS FOR THE SYNTHESIS OF 7-METHOXY-NAPHTHALENE-1-CARBALDEHYDE AND APPLICATION IN THE SYNTHESIS OF AGOMELATINE | LES LABORATOIRES SERVIER (FR) | 2016-10-20 | — | — | US | disclosed |
| EP-2077259-B1 | PROCESS FOR PRODUCTION OF 2,6-DIMETHYL-1-NAPHTHALDEHYDE | MITSUBISHI GAS CHEMICAL CO (JP) | 2013-05-08 | — | — | EP | disclosed |
| US-7902405-B2 | Process for production of 2,6-dimethyl-1-naphthaldehyde | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-03-08 | — | — | US | disclosed |
| US-20100004488-A1 | PROCESS FOR PRODUCTION OF 2,6-DIMETHYL-1-NAPHTHALDEHYDE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-2077259-A1 | PROCESS FOR PRODUCTION OF 2,6-DIMETHYL-1-NAPHTHALDEHYDE | Mitsubishi Gas Chemical Company, Inc. (JP) | 2009-07-08 | — | — | EP | disclosed |
| US-20050009903-A1 | CB2-selective cannabinoid analogues | CLEMSON UNIVERSITY | 2005-01-13 | — | — | US | disclosed |
| CN-1056485-A | The preparation method of naphthenone and/or cycloalkanol | STAMICARBON (NL) | 1991-11-27 | — | — | CN | disclosed |
| US-4112092-A | CNS DISORDER, PARKINSON'S, CARDIOVASCULAR DISORDER | SCIENCE UNION ET CIE (FR) | 1978-09-05 | — | — | US | disclosed |
| US-4018804-A | PROSTAGLANDINS AND DERIVATIVES | THE UPJOHN COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304429-A1 | PROCESS FOR THE SYNTHESIS OF 7-METHOXY-NAPHTHALENE-1-CARBALDEHYDE AND APPLICATION IN THE SYNTHESIS OF AGOMELATINE | COMT, TPH1, TPH2 | CYP2A6 74/4885CYP1A2 15/4885ALDH1A1 120/4885 |
| US-20050009903-A1 | CB2-selective cannabinoid analogues | CNR2, CNR1, GPR68 | CYP2A6 774/4885CYP1A2 825/4885ALDH1A1 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.