Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CBLB | Q13191 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13415944 | 0.98 | KMT2A (0.35) | KMT2AATMCBLBHTT | |
| Hydrochloric Acid SCHEMBL5332076 | 0.87 | GAA (0.38) | KMT2AATMCBLBHTT | |
| SCHEMBL14443968 | 0.85 | GAA (0.39) | KMT2AATMCBLBHTT | |
| Hydrochloric Acid SCHEMBL153335 | 0.84 | KMT2A (0.35) | KMT2AATMCBLB | |
| SCHEMBL154890 | 0.83 | KMT2A (0.36) | KMT2AATMCBLB | |
| SCHEMBL19484356 | 0.83 | BBOX1 (0.37) | KMT2AATMCBLB | |
| SCHEMBL21783321 | 0.82 | CBLB (0.43) | KMT2AATMCBLBHTT | |
| Hydrochloric Acid SCHEMBL6117375 | 0.81 | BBOX1 (0.42) | KMT2AATMCBLBHTT | |
| SCHEMBL23375507 | 0.80 | CBLB (0.42) | KMT2AATMCBLBHTT | |
| SCHEMBL19458462 | 0.80 | CBLB (0.42) | KMT2AATMCBLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539676-B1 | MONOMER COMPOUND COMPRISING SEVERAL CATIONIC GROUPS, PROCESS FOR MAKING THE SAME, AND POLYMERS COMPRISING UNITS DERIVING THEREFROM | SOLVAY USA INC (US) | 2017-07-26 | — | — | EP | disclosed |
| US-20160287509-A1 | Personal Care Compositions Containing Cationic Synthetic Copolymer and a Detersive Surfactant | PROCTER & GAMBLE (US) | 2016-10-06 | — | — | US | disclosed |
| US-9427391-B2 | Personal care compositions containing cationic synthetic copolymer and a detersive surfactant | THE PROCTER & GAMBLE COMPANY (US) | 2016-08-30 | — | — | US | disclosed |
| EP-2644592-A1 | Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom | RHODIA INC. (US) | 2013-10-02 | — | — | EP | disclosed |
| EP-2442787-A2 | PERSONAL CARE COMPOSITION COMPRISING A SYNTHETIC CATIONIC POLYMER | The Procter & Gamble Company (US) | 2012-04-25 | — | — | EP | disclosed |
| US-20100322878-A1 | Personal Care Composition Comprising a Synthetic Cationic Polymer | THE PROCTER & GAMBLE COMPANY | 2010-12-23 | — | — | US | disclosed |
| WO-2010148220-A2 | PERSONAL CARE COMPOSITION COMPRISING A SYNTHETIC CATIONIC POLYMER | THE PROCTER & GAMBLE COMPANY (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010080167-A2 | PERSONAL CARE COMPOSITIONS CONTAINING CATIONIC SYNTHETIC COPOLYMER AND A DETERSIVE SURFACTANT | THE PROCTER & GAMBLE COMPANY (US) | 2010-07-15 | — | — | WO | disclosed |
| WO-2009117569-A2 | PERSONAL CARE COMPOSITIONS CONTAINING CATIONIC SYNTHETIC COPOLYMER AND A DETERSIVE SURFACTANT | THE PROCTER & GAMBLE COMPANY (US) | 2009-09-24 | — | — | WO | disclosed |
| US-20090176675-A1 | Personal Care Compositions Containing Cationically Modified Starch and an Anionic Surfactant System | THE PROCTER & GAMBLE COMPANY | 2009-07-09 | — | — | US | disclosed |
| US-20080206179-A1 | Personal Care Compositions Containing Cationic Synthetic Copolymer and a Detersive Surfactant | PROCTER & GAMBLE COMPANY, THE | 2008-08-28 | — | — | US | disclosed |
| US-20070207109-A1 | Personal care compositions containing cationic synthetic copolymer and a detersive surfactant | PROCTER & GAMBLE COMPANY, THE | 2007-09-06 | — | — | US | disclosed |
| US-7247693-B2 | Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom | RHODIA INC. (US) | 2007-07-24 | — | — | US | disclosed |
| WO-2007080538-A2 | PERSONAL CARE COMPOSITIONS CONTAINING CATIONIC SYNTHETIC COPOLYMER AND A DETERSIVE SURFACTANT | THE PROCTER & GAMBLE COMPANY (US) | 2007-07-19 | — | — | WO | disclosed |
| EP-1539676-A4 | MONOMER COMPOUND COMPRISING SEVERAL CATIONIC GROUPS, PROCESS FOR MAKING THE SAME, AND POLYMERS COMPRISING UNITS DERIVING THEREFROM | RHODIA (US) | 2007-02-21 | — | — | EP | disclosed |
| US-20060111533-A1 | Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom | RHODIA OPERATIONS (FR) | 2006-05-25 | — | — | US | disclosed |
| US-7030275-B2 | Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom | RHODIA INC. (US) | 2006-04-18 | — | — | US | disclosed |
| EP-1539676-A1 | MONOMER COMPOUND COMPRISING SEVERAL CATIONIC GROUPS, PROCESS FOR MAKING THE SAME, AND POLYMERS COMPRISING UNITS DERIVING THEREFROM | Rhodia Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040010106-A1 | Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom | RHODIA OPERATIONS (FR) | 2004-01-15 | — | — | US | disclosed |
| WO-2003101935-A1 | MONOMER COMPOUND COMPRISING SEVERAL CATIONIC GROUPS, PROCESS FOR MAKING THE SAME, AND POLYMERS COMPRISING UNITS DERIVING THEREFROM | RHODIA INC. (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100322878-A1 | Personal Care Composition Comprising a Synthetic Cationic Polymer | PARN, PARG, PUF60 | KMT2A 4105/4885ATM 1181/4885CBLB 2942/4885 |
| US-20090176675-A1 | Personal Care Compositions Containing Cationically Modified Starch and an Anionic Surfactant System | CUTA, SCLY, MC1R | KMT2A 2181/4885ATM 2133/4885CBLB 1918/4885 |
| US-20080206179-A1 | Personal Care Compositions Containing Cationic Synthetic Copolymer and a Detersive Surfactant | C5, C3AR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | KMT2A 4265/4885ATM 2327/4885CBLB 594/4885 |
| US-20160287509-A1 | Personal Care Compositions Containing Cationic Synthetic Copolymer and a Detersive Surfactant | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CFH, C9 | KMT2A 3369/4885ATM 3047/4885CBLB 2576/4885 |
| US-20070207109-A1 | Personal care compositions containing cationic synthetic copolymer and a detersive surfactant | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CFH, C9 | KMT2A 3369/4885ATM 3047/4885CBLB 2576/4885 |
| US-20040010106-A1 | Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom | PCNA, PBRM1, B2M | KMT2A 894/4885ATM 4425/4885CBLB 2540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.