Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CBLB | Q13191 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14443968 | 0.99 | GAA (0.39) | GAAMGAMSIMGAM2KMT2A | |
| Hydrochloric Acid SCHEMBL2124456 | 0.87 | KMT2A (0.34) | KMT2AATMHTTCBLB | |
| SCHEMBL13415944 | 0.85 | KMT2A (0.35) | GAAMGAMSIMGAM2KMT2A | |
| Hydrochloric Acid SCHEMBL153335 | 0.81 | KMT2A (0.35) | KMT2AKDM4EATMACHELMNA | |
| Hydrochloric Acid SCHEMBL6117375 | 0.81 | BBOX1 (0.42) | KMT2AKDM4EATMRAD52ACHE | |
| SCHEMBL154890 | 0.79 | KMT2A (0.36) | KMT2AKDM4EATMLMNAALDH1A1 | |
| SCHEMBL19484356 | 0.79 | BBOX1 (0.37) | KMT2AKDM4EATMCBLB | |
| Hydrochloric Acid SCHEMBL31536719 | 0.79 | DNM1 (0.39) | KMT2AATMACHEHTTTSHR | |
| SCHEMBL22116247 | 0.79 | ZDHHC20 (0.47) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL3764634 | 0.79 | BBOX1 (0.43) | KMT2AKDM4EATMRAD52HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539676-B1 | MONOMER COMPOUND COMPRISING SEVERAL CATIONIC GROUPS, PROCESS FOR MAKING THE SAME, AND POLYMERS COMPRISING UNITS DERIVING THEREFROM | SOLVAY USA INC (US) | 2017-07-26 | — | — | EP | disclosed |
| EP-2644592-A1 | Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom | RHODIA INC. (US) | 2013-10-02 | — | — | EP | disclosed |
| US-7247693-B2 | Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom | RHODIA INC. (US) | 2007-07-24 | — | — | US | disclosed |
| EP-1539676-A4 | MONOMER COMPOUND COMPRISING SEVERAL CATIONIC GROUPS, PROCESS FOR MAKING THE SAME, AND POLYMERS COMPRISING UNITS DERIVING THEREFROM | RHODIA (US) | 2007-02-21 | — | — | EP | disclosed |
| US-20060111533-A1 | Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom | RHODIA OPERATIONS (FR) | 2006-05-25 | — | — | US | disclosed |
| US-7030275-B2 | Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom | RHODIA INC. (US) | 2006-04-18 | — | — | US | disclosed |
| EP-1539676-A1 | MONOMER COMPOUND COMPRISING SEVERAL CATIONIC GROUPS, PROCESS FOR MAKING THE SAME, AND POLYMERS COMPRISING UNITS DERIVING THEREFROM | Rhodia Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040010106-A1 | Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom | RHODIA OPERATIONS (FR) | 2004-01-15 | — | — | US | disclosed |
| WO-2003101935-A1 | MONOMER COMPOUND COMPRISING SEVERAL CATIONIC GROUPS, PROCESS FOR MAKING THE SAME, AND POLYMERS COMPRISING UNITS DERIVING THEREFROM | RHODIA INC. (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010106-A1 | Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom | PCNA, PBRM1, B2M | ACHE 3600/4885GAA 4211/4885MGAM 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.