SCHEMBL212463

SCHEMBL212463

O=C(c1ccccc1)c1c2ccccc2cc2ccccc12

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.69
KMT2A Q03164 5/20 0.69
ALDH1A1 P00352 4/20 0.69
HPGD P15428 2/20 0.69
KDM4E B2RXH2 1/20 0.69
CYP1A2 P05177 1/20 0.69
GLA P06280 1/20 0.69
CYP2C19 P33261 1/20 0.69
HSD17B10 Q99714 1/20 0.69
ATM Q13315 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
HTT P42858 1/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
ACACB O00763 1/20 0.47
ACACA Q13085 1/20 0.47
SRD5A2 P31213 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31177917 1.00 MEN1 (0.69) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL1667099 0.84 ALDH1A1 (0.55) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL9350261 0.84 MEN1 (0.50) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL7918712 0.84 ALDH1A1 (0.68) MEN1KMT2AALDH1A1CYP2C19HSD17B10
SCHEMBL28909397 0.83 MEN1 (0.58) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL11484901 0.83 BCL2L1 (0.56) MEN1KMT2AALDH1A1HPGDKDM4E
Anthracene-9-Carboxylic Acid SCHEMBL29352186 0.82 MEN1 (1.00) MEN1KMT2AALDH1A1HPGDKDM4E
Anthracene-9-Carboxylic Acid SCHEMBL122832 0.82 MEN1 (1.00) MEN1KMT2AALDH1A1HPGDKDM4E
Benzophenone SCHEMBL2577611 0.81 ALDH1A1 (0.74) MEN1KMT2AALDH1A1HPGDATM
SCHEMBL28909399 0.81 KDM4E (0.61) MEN1KMT2AALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3109703-B1 PHOTOSENSITIZATION CHEMICAL-AMPLIFICATION TYPE RESIST MATERIAL, AND METHOD FOR FORMING PATTERN USING SAME TOKYO ELECTRON LTD (JP) 2020-12-30 EP disclosed
US-10025187-B2 Photosensitization chemical-amplification type resist material, method for forming pattern using same, semiconductor device, mask for lithography, and template for nanoimprinting TOKYO ELECTRON LIMITED (JP) 2018-07-17 US disclosed
US-10025187-B2 Photosensitization chemical-amplification type resist material, method for forming pattern using same, semiconductor device, mask for lithography, and template for nanoimprinting TOKYO ELECTRON LIMITED (JP) 2018-07-17 US disclosed
US-10018911-B2 Chemically amplified resist material and resist pattern-forming method JSR CORPORATION (JP) 2018-07-10 US disclosed
US-10018911-B2 Chemically amplified resist material and resist pattern-forming method JSR CORPORATION (JP) 2018-07-10 US disclosed
US-9971247-B2 Pattern-forming method OSAKA UNIVERSITY (JP) 2018-05-15 US disclosed
US-20170131633-A1 CHEMICALLY AMPLIFIED RESIST MATERIAL AND RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2017-05-11 US disclosed
US-20170131633-A1 CHEMICALLY AMPLIFIED RESIST MATERIAL AND RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2017-05-11 US disclosed
US-20170052449-A1 CHEMICALLY AMPLIFIED RESIST MATERIAL, PATTERN-FORMING METHOD, COMPOUND, AND PRODUCTION METHOD OF COMPOUND OSAKA UNIVERSITY (JP) 2017-02-23 US disclosed
US-20170052448-A1 RESIST-PATTERN-FORMING METHOD AND CHEMICALLY AMPLIFIED RESIST MATERIAL OSAKA UNIVERSITY (JP) 2017-02-23 US disclosed
US-4383089-A Process for the production of polyepoxy silicate resin BLOUNT DAVID H 1983-05-10 US disclosed
US-4383049-A POLYURETHANES BLOUNT DAVID H 1983-05-10 US disclosed
US-4377646-A REACTING AN EPOXY COMPOUND, SILICIC ACID, AND A POLYISOCYANATE USING A LEWIS ACID CATALYST; POLYURETHANES; INSULATION BLOUNT DAVID H 1983-03-22 US disclosed
US-4376173-A LIGNIN, CELLULOSE, POLYURETHANE FOAM, POLYISOCYANATE BLOUNT DAVID H 1983-03-08 US disclosed
US-4367326-A Process for the production of polyepoxy silicate resins DORSEY & WHITNEY LLP 1983-01-04 US disclosed
US-4367273-A Electrophotographic plate comprising a conductive substrate and a photosensitive layer containing an organic photoconductor layer composed of a hydrazone compound MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1983-01-04 US disclosed
US-4357463-A HEATING A SILICON COMPOUND, AN EPOXIDE, A DICARBOXYLIC ACID OR ANHYDRIDE, AND A LEWIS ACID; COATINGS; MOLDING MATERIALS; ADHESIVES BLOUNT DAVID H 1982-11-02 US disclosed
EP-0063387-A1 Electrophotographic plate MITSUBISHI KASEI CORPORATION (JP) 1982-10-27 EP disclosed
US-4278747-A Electrophotographic plate comprising a conductive substrate and a photosensitive layer containing an organic photoconductor layer composed of a hydrazone compound MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1981-07-14 US disclosed
US-3975196-A Photoconductive charge transfer complex for electrophotography PITNEY-BOWES, INC. (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10025187-B2 Photosensitization chemical-amplification type resist material, method for forming pattern using same, semiconductor device, mask for lithography, and template for nanoimprinting ASIC1, ASIC3, CLTA MEN1 847/4885KMT2A 71/4885ALDH1A1 1963/4885
US-10018911-B2 Chemically amplified resist material and resist pattern-forming method SLC11A2, XRCC5, RAD54L MEN1 455/4885KMT2A 1432/4885ALDH1A1 2183/4885
US-20170052449-A1 CHEMICALLY AMPLIFIED RESIST MATERIAL, PATTERN-FORMING METHOD, COMPOUND, AND PRODUCTION METHOD OF COMPOUND RER1, POLR1A, FEM1B MEN1 742/4885KMT2A 737/4885ALDH1A1 1044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.