Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.43 |
| ▸ | WEE1 | P30291 | 2/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766596 | 0.87 | MAPT (0.55) | CHEK1WEE1ADKHTTTYMP | |
| SCHEMBL24511038 | 0.80 | LMNA (0.48) | HTTTYMPLMNAMAPTKDM4E | |
| SCHEMBL11304603 | 0.78 | LMNA (0.46) | HTTTYMPLMNAMAPTKDM4E | |
| SCHEMBL28213146 | 0.73 | MAOA (0.46) | MAOACHEK1WEE1ADKGSK3B | |
| SCHEMBL29731800 | 0.73 | LMNA (0.46) | HTTTYMPLMNAMAPTKDM4E | |
| SCHEMBL10519343 | 0.72 | ALDH1A1 (0.54) | HTTTYMPLMNAMAPTCA1 | |
| SCHEMBL369310 | 0.72 | UCHL1 (0.43) | MAOAGSK3BPTGS2 | |
| SCHEMBL15655133 | 0.72 | LMNA (0.50) | MAOAHTTTYMPLMNAMAPT | |
| SCHEMBL29414113 | 0.72 | UCHL1 (0.43) | MAOAGSK3BPTGS2 | |
| SCHEMBL28462021 | 0.72 | CYP3A4 (0.46) | MAOACHEK1WEE1HTTGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019153135-A1 | POLY(ARYL ETHER SULFONE)-ETHER IMIDE COPOLYMER AND PREPARATION METHOD THEREFOR | 江门市优巨新材料有限公司 | 2019-08-15 | — | — | WO | disclosed |