Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21246887 | 0.81 | PRMT1 (0.44) | ADRB1ADRB2SIGMAR1ADRB3 | |
| SCHEMBL21259413 | 0.80 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1ADRB1OPRK1 | |
| SCHEMBL21259429 | 0.80 | KMT2A (0.49) | ALDH1A1KMT2AMEN1ADRB1OPRK1 | |
| SCHEMBL21259419 | 0.74 | CYP2D6 (0.46) | ALDH1A1KMT2AMEN1ADRB1ADRB2 | |
| SCHEMBL10555636 | 0.73 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1ADRB1OPRK1 | |
| SCHEMBL21246874 | 0.71 | KMT2A (0.64) | ALDH1A1KMT2AMEN1ADRB1OPRK1 | |
| SCHEMBL28698888 | 0.69 | GPR84 (0.49) | KMT2AMEN1ADRB1KDM4EADRA2A | |
| Hydrochloric Acid SCHEMBL11480657 | 0.69 | ADRB2 (0.68) | ALDH1A1KMT2AMEN1ADRB1OPRK1 | |
| Hydrochloric Acid SCHEMBL11480654 | 0.69 | ADRB2 (0.68) | ALDH1A1KMT2AMEN1ADRB1OPRK1 | |
| SCHEMBL2278702 | 0.68 | KDR (0.52) | KMT2AMEN1HSD17B10LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019153216-A1 | SUBSTITUTED ARYLAMINO ALCOHOL COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 北京梅尔森医药技术开发有限公司 | 2019-08-15 | — | — | WO | claimed |
| CN-108299279-B | Substituted arylaminol compounds, methods of making, and uses thereof | 北京梅尔森医药技术开发有限公司 | 2021-03-23 | — | — | CN | disclosed |
| WO-2019153216-A1 | SUBSTITUTED ARYLAMINO ALCOHOL COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 北京梅尔森医药技术开发有限公司 | 2019-08-15 | — | — | WO | disclosed |
| WO-2019153216-A1 | SUBSTITUTED ARYLAMINO ALCOHOL COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 北京梅尔森医药技术开发有限公司 | 2019-08-15 | — | — | WO | disclosed |