Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | FFAR2 | O15552 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | STK10 | O94804 | 1/20 | 0.50 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27847027 | 0.96 | ATM (0.56) | XDHATMFFAR2MAPTL3MBTL1 | |
| SCHEMBL1222758 | 0.87 | RXRA (0.58) | XDHFFAR2HPGDPPARGPPARA | |
| SCHEMBL12189290 | 0.87 | L3MBTL1 (0.60) | PTPRCPTPN1XDHFFAR2MAPT | |
| SCHEMBL29788043 | 0.86 | EGFR (0.56) | PTPRCPTPN1XDHFFAR2MAPT | |
| SCHEMBL2050621 | 0.86 | EGFR (0.56) | PTPRCPTPN1XDHFFAR2MAPT | |
| SCHEMBL2039480 | 0.86 | FFAR2 (0.49) | PTPRCPTPN1XDHFFAR2L3MBTL1 | |
| SCHEMBL2967361 | 0.86 | MAPK8 (0.58) | PTPRCPTPN1XDHFFAR2L3MBTL1 | |
| SCHEMBL27499555 | 0.84 | LMNA (0.58) | ATMMAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL14685999 | 0.83 | CYP1A2 (0.65) | ATMMAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL15709668 | 0.83 | CYP1A2 (0.53) | PTPRCPTPN1XDHFFAR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094557-B | Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohol | 江南大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-111433357-B | Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohol | 江南大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-111433357-A | Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohol | 江南大学 | 2020-07-17 | — | — | CN | disclosed |
| WO-2019153634-A1 | ALCOHOL DEHYDROGENASE MUTANT AND APPLICATION THEREOF IN SYNTHESIS OF BIARYL CHIRAL ALCOHOL | 江南大学 | 2019-08-15 | — | — | WO | disclosed |
| WO-2019153633-A1 | ALCOHOL DEHYDROGENASE MUTANT AND APPLICATION THEREOF IN SYNTHEISIS OF DIARYL CHIRAL ALCOHOL | 江南大学 | 2019-08-15 | — | — | WO | disclosed |
| WO-2019153632-A1 | ALCOHOL DEHYDROGENASE MUTANT AND APPLICATION THEREOF IN SYNTHEISIS OF DIARYL CHIRAL ALCOHOL | 江南大学 | 2019-08-15 | — | — | WO | disclosed |