Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | PTPRC | P08575 | 2/20 | 0.54 |
| ▸ | PTPRF | P10586 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | VDR | P11473 | 1/20 | 0.49 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2050621 | 1.00 | EGFR (0.56) | EGFRTSHRPTPN1PTPRCPTPRF | |
| SCHEMBL21246919 | 0.86 | PTPRC (0.51) | TSHRPTPN1PTPRCMAPTLMNA | |
| SCHEMBL6535966 | 0.85 | ADORA3 (0.50) | EGFRTSHRPTPN1PTPRCPTPRF | |
| SCHEMBL3508583 | 0.85 | POLB (0.55) | TSHRPTPN1PTPRCSLC6A3MAPT | |
| SCHEMBL1222758 | 0.84 | RXRA (0.58) | EGFRCA1CA2FFAR2XDH | |
| SCHEMBL12189290 | 0.84 | L3MBTL1 (0.60) | PTPN1PTPRCMAPTLMNASMN1; SMN2 | |
| SCHEMBL15999083 | 0.84 | PTPN1 (0.52) | EGFRTSHRPTPN1PTPRCPTPRF | |
| SCHEMBL4146550 | 0.84 | MAPT (0.55) | PTPN1CA1CA2MAPTLMNA | |
| SCHEMBL27708108 | 0.84 | EGFR (0.71) | EGFRTSHRPTPN1PTPRCPTPRF | |
| SCHEMBL5944253 | 0.83 | HDAC6 (0.60) | CA1CA2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013017-A | Pharmaceutical composition for treating cancer comprising an anticancer agent and a novel compound having an inhibitory activity on prostaglandin E2 receptor | 治纳辅医药科技有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-114773249-B | Compounds, pharmaceutical compositions and methods for treating inflammatory diseases | 艾匹克治疗公司 | 2024-08-16 | — | — | CN | disclosed |
| WO-2023158221-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, COMPRISING ANTICANCER AGENT AND NOVEL COMPOUND HAVING INHIBITORY ACTIVITY WITH RESPECT TO PROSTAGLANDIN E2 RECEPTORS | 주식회사 카나프테라퓨틱스 | 2023-08-24 | — | — | WO | disclosed |
| CN-114773249-A | Compounds, pharmaceutical compositions and methods for treating inflammatory diseases | 艾匹克治疗公司 | 2022-07-22 | — | — | CN | disclosed |