Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15586578 | 0.82 | TYR (0.52) | ERN1MAPTKDM4EALDH1A1ALOX5 | |
| SCHEMBL11587871 | 0.79 | TYR (0.54) | MAPTKDM4EALDH1A1ALOX5ALOX15 | |
| SCHEMBL2987385 | 0.79 | TYR (0.47) | CA2MAPTKDM4EALDH1A1ALOX5 | |
| SCHEMBL2120782 | 0.79 | KLF10 (0.50) | ERN1MAPTALOX15KLF10MEN1 | |
| SCHEMBL9467640 | 0.78 | ALOX5 (0.50) | ERN1MAPTALOX5BACE1TYR | |
| SCHEMBL2122564 | 0.76 | TSHR (0.46) | ERN1CA2KDM4EALDH1A1ALOX15 | |
| SCHEMBL9277050 | 0.76 | AMY1A (0.53) | MAPTALDH1A1GAABACE1ALOX15 | |
| SCHEMBL11042437 | 0.76 | PRKCI (0.52) | CA2MAPTKDM4EALDH1A1ALOX5 | |
| SCHEMBL6491986 | 0.74 | TNKS2 (0.44) | KDM4EMTNR1AMTNR1BSLC6A4 | |
| SCHEMBL31596382 | 0.73 | TYR (0.47) | MAPTKDM4EALDH1A1ALOX5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094939-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS AND METHODS | TRUSTEES OF BOSTON UNIVERSITY | 2012-04-19 | — | — | US | disclosed |
| US-20120094939-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS AND METHODS | TRUSTEES OF BOSTON UNIVERSITY | 2012-04-19 | — | — | US | disclosed |
| US-20120094939-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS AND METHODS | TRUSTEES OF BOSTON UNIVERSITY | 2012-04-19 | — | — | US | disclosed |
| WO-2008124571-A2 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS AND METHODS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008124571-A2 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS AND METHODS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094939-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS AND METHODS | HAVCR2, EIF2AK2, RPL35 | ERN1 1211/4885CA2 4229/4885MAPT 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.