SCHEMBL20625867

SCHEMBL20625867

C=N/C(=C\C(=C/C)c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ AKT1 P31749 1/20 0.32
▸ ATM Q13315 1/20 0.31
▸ NFE2L2 Q16236 1/20 0.31
▸ CA12 O43570 1/20 0.31
▸ CA1 P00915 1/20 0.31
▸ CA2 P00918 1/20 0.31
▸ CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19300441 0.81 AKT1 (0.38) MEN1KMT2ALMNAMAPK1HTT
SCHEMBL22071895 0.81 LMNA (0.36) MEN1KMT2ALMNAMAPK1HTT
SCHEMBL24884816 0.78 AKT1 (0.35) MEN1KMT2ALMNAMAPK1HTT
SCHEMBL21229634 0.77 MAPT (0.43) MEN1KMT2ALMNAMAPK1L3MBTL1
SCHEMBL22036325 0.77 LMNA (0.36) MEN1KMT2ALMNAMAPK1HTT
SCHEMBL20908860 0.76 MEN1 (0.32) MEN1KMT2ALMNAMAPK1HTT
SCHEMBL21253891 0.75 AKT1 (0.37) MEN1KMT2AMAPK1AKT1ATM
SCHEMBL19446503 0.74 CES2 (0.37) MEN1KMT2AMAPK1NFE2L2CA12
SCHEMBL19101609 0.73 TSHR (0.32) MEN1KMT2ALMNAMAPK1L3MBTL1
SCHEMBL24520419 0.73 NFE2L2 (0.52) MEN1KMT2AMAPK1HTTAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10177316-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-01-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10177316-B2 Organic electroluminescent materials and devices OSBP, OSBPL3, OSBP2 MEN1 4195/4885KMT2A 4410/4885LMNA 3670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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