Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | MC4R | P32245 | 1/20 | 0.64 |
| ▸ | SCN4A | P35499 | 1/20 | 0.64 |
| ▸ | MC3R | P41968 | 1/20 | 0.64 |
| ▸ | HTR3A | P46098 | 1/20 | 0.64 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.64 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.64 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16709550 | 0.88 | LMNA (0.82) | ALDH1A1LMNAMAPTMAPK1CYP3A4 | |
| SCHEMBL2097382 | 0.84 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPTMAPK1CYP3A4 | |
| SCHEMBL18072316 | 0.84 | MAPT (0.55) | ALDH1A1LMNAMAPTMAPK1CYP3A4 | |
| SCHEMBL21264151 | 0.83 | LMNA (0.74) | ALDH1A1LMNAMAPTMAPK1CYP3A4 | |
| SCHEMBL21264241 | 0.82 | LMNA (0.77) | ALDH1A1LMNAMAPTMAPK1CYP3A4 | |
| SCHEMBL21261870 | 0.82 | LMNA (0.72) | ALDH1A1LMNAMAPTMAPK1CYP3A4 | |
| SCHEMBL23222281 | 0.81 | ALDH1A1 (0.70) | ALDH1A1LMNAMAPTMAPK1GAA | |
| SCHEMBL12994774 | 0.81 | MAPT (0.74) | ALDH1A1LMNAMAPTMAPK1CYP3A4 | |
| SCHEMBL16677167 | 0.80 | MAPT (0.78) | ALDH1A1LMNAMAPTMAPK1CYP3A4 | |
| SCHEMBL7532501 | 0.80 | PKM (0.56) | ALDH1A1LMNAMAPTMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11697639-B2 | Quaternary ammonium salt compound, preparation method therefor and use thereof | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2023-07-11 | — | — | US | disclosed |
| US-20210107872-A1 | QUATERNARY AMMONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2021-04-15 | — | — | US | disclosed |
| WO-2019154287-A1 | QUATERNARY AMMONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川大学华西医院 | 2019-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11697639-B2 | Quaternary ammonium salt compound, preparation method therefor and use thereof | SCN11A, SLC6A11, SCN8A | ALDH1A1 2705/4885LMNA 3589/4885MAPT 2140/4885 |
| US-20210107872-A1 | QUATERNARY AMMONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SCN11A, SLC6A11, SCN8A | ALDH1A1 2705/4885LMNA 3589/4885MAPT 2140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.