Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30876131 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KMT2APTK2BP4HTMEGLN1 | |
| SCHEMBL31500545 | 0.87 | P4HTM (0.48) | KMT2APTK2BP4HTMNR4A1NR4A2 | |
| SCHEMBL21248064 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KMT2APTK2BHTTSMN1; SMN2 | |
| SCHEMBL21248153 | 0.76 | MAPT (0.44) | ALDH1A1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL30876104 | 0.76 | MAPT (0.44) | ALDH1A1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL16610000 | 0.72 | TSHR (0.58) | ALDH1A1KMT2APTK2BTSHRLMNA | |
| SCHEMBL21248383 | 0.71 | CYP1A2 (0.44) | ALDH1A1KMT2APTK2BP4HTMEGLN1 | |
| SCHEMBL16594423 | 0.70 | TSHR (0.56) | ALDH1A1KMT2APTK2BSMN1; SMN2TSHR | |
| SCHEMBL16594604 | 0.70 | TSHR (0.56) | ALDH1A1KMT2APTK2BSMN1; SMN2TSHR | |
| SCHEMBL21184469 | 0.70 | TSHR (0.56) | ALDH1A1KMT2APTK2BSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111683950-B | AhR modulators | 伊迪亚生物科学有限公司 | 2024-04-16 | — | — | CN | disclosed |
| EP-4219495-A1 | AHR MODULATORS | Ideaya Biosciences, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| US-20230039955-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
| US-11407764-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2022-08-09 | — | — | US | disclosed |
| US-20210002297-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2021-01-07 | — | — | US | disclosed |
| US-10815250-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2020-10-27 | — | — | US | disclosed |
| CN-111683950-A | AhR modulators | 伊迪亚生物科学有限公司 | 2020-09-18 | — | — | CN | disclosed |
| US-20190270754-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2019-09-05 | — | — | US | disclosed |
| WO-2019156987-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. (US) | 2019-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11407764-B2 | AhR modulators | AHR, ARNT, RORB | ALDH1A1 579/4885KMT2A 306/4885PTK2B 2284/4885 |
| US-20230039955-A1 | AhR MODULATORS | AHR, ARNT, RORB | ALDH1A1 584/4885KMT2A 314/4885PTK2B 2260/4885 |
| US-10815250-B2 | AhR modulators | AHR, ARNT, RORB | ALDH1A1 579/4885KMT2A 306/4885PTK2B 2284/4885 |
| US-20210002297-A1 | AhR MODULATORS | AHR, ARNT, RORB | ALDH1A1 579/4885KMT2A 306/4885PTK2B 2284/4885 |
| US-20190270754-A1 | AhR MODULATORS | AHR, ARNT, RORB | ALDH1A1 579/4885KMT2A 306/4885PTK2B 2284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.