Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2426791 | 0.86 | LTA4H (0.58) | ALDH1A1PTK2BLTA4HMAPK14PPIA | |
| SCHEMBL30848623 | 0.86 | LTA4H (0.58) | ALDH1A1PTK2BLTA4HMAPK14PPIA | |
| Hydrochloric Acid SCHEMBL10705444 | 0.85 | LTA4H (0.57) | ALDH1A1PTK2BLTA4HMAPK14PPIA | |
| SCHEMBL8883428 | 0.84 | CYP11B1 (0.55) | ALDH1A1KMT2AKDM4EMAPTCYP3A4 | |
| SCHEMBL8883103 | 0.82 | ASPH (0.49) | ALDH1A1KMT2AKDM4EMAPTCYP3A4 | |
| SCHEMBL8882396 | 0.81 | ASPH (0.50) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL21265705 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KMT2APTK2BKDM4ETSHR | |
| SCHEMBL30876131 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KMT2APTK2BKDM4ETSHR | |
| SCHEMBL796628 | 0.79 | KDM4E (0.47) | ALDH1A1KMT2APTK2BKDM4EMAPT | |
| SCHEMBL1138239 | 0.79 | KDM4E (0.50) | ALDH1A1KMT2APTK2BKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12258354-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2025-03-25 | — | — | US | disclosed |
| EP-3749669-B3 | AHR MODULATORS | IDEAYA BIOSCIENCES INC (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-111683950-B | AhR modulators | 伊迪亚生物科学有限公司 | 2024-04-16 | — | — | CN | disclosed |
| EP-4219495-A1 | AHR MODULATORS | Ideaya Biosciences, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-4219495-A1 | AHR MODULATORS | Ideaya Biosciences, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3749669-B1 | AHR MODULATORS | IDEAYA BIOSCIENCES INC (US) | 2023-03-08 | — | — | EP | disclosed |
| US-20230039955-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
| US-20230039955-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
| US-11407764-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2022-08-09 | — | — | US | disclosed |
| US-11407764-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2022-08-09 | — | — | US | disclosed |
| US-20210002297-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2021-01-07 | — | — | US | disclosed |
| US-20210002297-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2021-01-07 | — | — | US | disclosed |
| EP-3749669-A1 | AHR MODULATORS | Ideaya Biosciences, Inc. (US) | 2020-12-16 | — | — | EP | disclosed |
| US-10815250-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2020-10-27 | — | — | US | disclosed |
| US-10815250-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2020-10-27 | — | — | US | disclosed |
| CN-111683950-A | AhR modulators | 伊迪亚生物科学有限公司 | 2020-09-18 | — | — | CN | disclosed |
| US-20190270754-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2019-09-05 | — | — | US | disclosed |
| US-20190270754-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2019-09-05 | — | — | US | disclosed |
| WO-2019156987-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. (US) | 2019-08-15 | — | — | WO | disclosed |
| WO-2019156987-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. (US) | 2019-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11407764-B2 | AhR modulators | AHR, ARNT, RORB | ALDH1A1 579/4885KMT2A 306/4885PTK2B 2284/4885 |
| US-20230039955-A1 | AhR MODULATORS | AHR, ARNT, RORB | ALDH1A1 584/4885KMT2A 314/4885PTK2B 2260/4885 |
| US-12258354-B2 | AhR modulators | AHR, ARNT, RORB | ALDH1A1 579/4885KMT2A 306/4885PTK2B 2284/4885 |
| US-10815250-B2 | AhR modulators | AHR, ARNT, RORB | ALDH1A1 579/4885KMT2A 306/4885PTK2B 2284/4885 |
| US-20210002297-A1 | AhR MODULATORS | AHR, ARNT, RORB | ALDH1A1 579/4885KMT2A 306/4885PTK2B 2284/4885 |
| US-20190270754-A1 | AhR MODULATORS | AHR, ARNT, RORB | ALDH1A1 579/4885KMT2A 306/4885PTK2B 2284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.