Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.31 |
| ▸ | SLC16A1 | P53985 | 4/20 | 0.31 |
| ▸ | MCTS1 | Q9ULC4 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126352 | 0.97 | ALDH1A1 (0.33) | HSP90AA1HSP90AB1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL2125479 | 0.87 | ACLY (0.37) | ALDH1A1CYP3A4KMT2AMEN1SLC16A3 | |
| SCHEMBL2126498 | 0.84 | ACLY (0.41) | ALDH1A1CYP3A4SLC16A3SLC16A1MCTS1 | |
| SCHEMBL2127428 | 0.83 | KDM4E (0.32) | ALDH1A1KMT2AMEN1TAAR1 | |
| SCHEMBL2126333 | 0.83 | KDM4E (0.31) | ALDH1A1KMT2AMEN1TAAR1 | |
| SCHEMBL1282998 | 0.82 | L3MBTL1 (0.38) | ALDH1A1CYP3A4KMT2AL3MBTL1MEN1 | |
| SCHEMBL2125668 | 0.82 | ALDH1A1 (0.31) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL1283614 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP3A4KMT2AMEN1SLC16A3 | |
| SCHEMBL1282504 | 0.81 | L3MBTL1 (0.37) | ALDH1A1CYP3A4KMT2AL3MBTL1MEN1 | |
| SCHEMBL15371830 | 0.80 | ALDH1A1 (0.35) | ALDH1A1CYP3A4KMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108422-A1 | Antifungal 1,2,4-triazolyl Derivatives | BASF SE (DE) | 2012-05-03 | — | — | US | disclosed |
| EP-2443097-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146111-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES | BASF SE (DE) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108422-A1 | Antifungal 1,2,4-triazolyl Derivatives | ERG28, CYP51A1, DPM1 | HSP90AA1 2283/4885HSP90AB1 1662/4885ALDH1A1 1943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.