Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282504 | 0.99 | L3MBTL1 (0.37) | L3MBTL1MAPTTDP1CYP1A2CYP2C19 | |
| SCHEMBL1286610 | 0.88 | GAA (0.44) | MAPTCYP1A2CYP2C19TSHRNPC1 | |
| SCHEMBL1283316 | 0.88 | L3MBTL1 (0.40) | L3MBTL1TDP1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL1281680 | 0.87 | GAA (0.44) | MAPTCYP1A2CYP2C19TSHRNPC1 | |
| SCHEMBL1282484 | 0.87 | L3MBTL1 (0.39) | L3MBTL1TDP1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL1281750 | 0.85 | DHFR (0.37) | NPC1RAB9APPARGPPARDPPARA | |
| SCHEMBL1282491 | 0.84 | GAA (0.45) | MAPTCYP1A2CYP2C19TSHRNPC1 | |
| SCHEMBL2126352 | 0.83 | ALDH1A1 (0.33) | L3MBTL1ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL1282373 | 0.83 | FDPS (0.37) | PPARAHRH3ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL2127221 | 0.82 | HSP90AA1 (0.36) | L3MBTL1ALDH1A1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088660-A1 | Antifungal 1,2,4-triazolyl Derivatives | BASF SE (DE) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088660-A1 | Antifungal 1,2,4-triazolyl Derivatives | ERG28, CYP51A1, DPM1 | L3MBTL1 3006/4885MAPT 1824/4885TDP1 3127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.