Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 7/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254371 | 1.00 | KDM4E (0.42) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL6267426 | 0.89 | CYP1A2 (0.43) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL7116753 | 0.84 | KDM4E (0.46) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL6255925 | 0.83 | CTNNB1 (0.36) | KDM4ELMNAPOLBCYP2A6SMN1; SMN2 | |
| SCHEMBL6254079 | 0.81 | HPGDS (0.39) | SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6266204 | 0.80 | CYP1A2 (0.44) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL6252860 | 0.80 | CCR1 (0.44) | KDM4ECCR1CCR5CCR8CYP2A6 | |
| SCHEMBL6252273 | 0.79 | KDM4E (0.41) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL21272268 | 0.79 | KDM4E (0.41) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL1054804 | 0.78 | ALDH1A1 (0.35) | MAPTHTTALDH1A1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143538-A1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | Chisso Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |