SCHEMBL2127293

SCHEMBL2127293

CC(=CNC(=O)O)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.34
AKR1C3 P42330 1/20 0.34
MAPT P10636 1/20 0.32
NFKB1 P19838 1/20 0.32
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
APEX1 P27695 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALDH1A1 P00352 1/20 0.30
GABRA1 P14867 1/20 0.30
TSHR P16473 1/20 0.30
GABRG2 P18507 1/20 0.30
RXRA P19793 1/20 0.30
GABRB3 P28472 1/20 0.30
RXRB P28702 1/20 0.30
GABRB2 P47870 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1324470 0.83 NFKB1 (0.38) PTGS1AKR1C3NFKB1FFAR3LCK
SCHEMBL9440074 0.83 NFKB1 (0.38) PTGS1AKR1C3NFKB1FFAR3LCK
SCHEMBL129220 0.79 CRBN (0.36) PTGS1AKR1C3NFKB1TSHR
SCHEMBL26884 0.79 CRBN (0.36) PTGS1AKR1C3NFKB1TSHR
SCHEMBL14018669 0.79 PTGS1 (0.32) PTGS1AKR1C3
SCHEMBL17105850 0.77 ALDH1A1 (0.39) MAPTALDH1A1
SCHEMBL11274085 0.77
SCHEMBL28959894 0.77 PTGS1 (0.37) PTGS1AKR1C3MAPTNFKB1FFAR3
SCHEMBL20537845 0.75 ALDH1A1 (0.39) ALDH1A1
SCHEMBL5702107 0.75 ALDH1A1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103804629-B Carbamate(Methyl)Acrylate mixture and carbamate(Methyl)Acrylate composition 日油株式会社 2017-12-15 CN claimed
CN-107073760-A Thermosetting in-mold finishing film 专展览公司 2017-08-18 CN claimed
US-9566216-B2 Bone cements containing magnetic calcium phosphate nanoparticles SOUTHWEST RESEARCH INSTITUTE (US) 2017-02-14 US claimed
US-20150142112-A1 Bone Cements Containing Magnetic Calcium Phosphate Nanoparticles SOUTHWEST RESEARCH INSTITUTE 2015-05-21 US claimed
CN-104419011-A Forming in-place gasket with tack free surface DYMAX CORP 2015-03-18 CN claimed
US-11359093-B2 Polyimide film and flexible display device cover substrate using the same MICROCOSM TECHNOLOGY CO., LTD. (TW) 2022-06-14 US disclosed
US-11220098-B2 Imageable coating layer, thermal negative-working lithography printing plate, and platemaking method therefor ZHEJIANG KONITA NEW MATERIALS CO., LTD. (CN) 2022-01-11 US disclosed
US-20210171769-A1 POLYIMIDE FILM AND FLEXIBLE DISPLAY DEVICE COVER SUBSTRATE USING THE SAME MICROCOSM TECHNOLOGY CO., LTD. (TW) 2021-06-10 US disclosed
US-20210165132-A1 FLEXIBLE DISPLAY COVER SUBSTRATE MICROCOSM TECHNOLOGY CO., LTD. (TW) 2021-06-03 US disclosed
CN-107592869-B RAFT agent, polymerization method, polymer, rubber mixture, and use thereof 大陆轮胎德国有限公司 2021-05-14 CN disclosed
EP-3501826-B1 IMAGEABLE COATING, THERMAL NEGATIVE-WORKING LITHOGRAPHY PRINTING PLATE, AND PLATEMAKING METHOD THEREFOR ZHEJIANG KONITA NEW MAT CO LTD (CN) 2021-03-17 EP disclosed
US-10442877-B2 Raft agent, polymerization method, polymer, rubber mixture, and use thereof CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2019-10-15 US disclosed
US-20100307378-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI-DENTAL DIVISION (US) 2010-12-09 US disclosed
CN-101747490-A Fluorine-containing resin, preparation method thereof, conformal coating and printed circuit board BYD CO LTD 2010-06-23 CN disclosed
WO-2010042818-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI-DENTAL DIVISION (US) 2010-04-15 WO disclosed
WO-2010042818-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI-DENTAL DIVISION (US) 2010-04-15 WO disclosed
US-20100038606-A1 BLACK RESIN COMPOSITION, RESIN BLACK MATRIX, COLOR FILTER AND LIQUID CRYSTAL DISPLAY TORAY INDUSTRIES, INC. (JP) 2010-02-18 US disclosed
EP-2135900-A1 BLACK RESIN COMPOSITION, RESIN BLACK MATRIX, COLOR FILTER AND LIQUID CRYSTAL DISPLAY Toray Industries, Inc. (JP) 2009-12-23 EP disclosed
CN-1255932-A Fluorochemical composition comprising polymer derived from fluorochemical urethane (meth) acrylate monomer to impart stain release properties to a substrate MINNESOTA MING AND MFG CO (US) 2000-06-07 CN disclosed
US-4690995-A Copolymers containing high concentrations of phenol antioxidant units THE DOW CHEMICAL COMPANY (US) 1987-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150142112-A1 Bone Cements Containing Magnetic Calcium Phosphate Nanoparticles ACP1, ACP3, BMP2 PTGS1 976/4885AKR1C3 3478/4885MAPT 112/4885
US-20100307378-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS CAD, ACMSD, MMAB PTGS1 2593/4885AKR1C3 1789/4885MAPT 775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.