Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.44 |
| ▸ | PRKACA | P17612 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.44 |
| ▸ | PRKX | P51817 | 2/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.44 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4177126 | 0.91 | MDM2 (0.44) | ERCC5FEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3316473 | 0.91 | MDM2 (0.44) | ERCC5FEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19661441 | 0.79 | CTSK (0.54) | — | |
| SCHEMBL3118546 | 0.77 | CTSS (0.44) | ALDH1A1 | |
| SCHEMBL12985717 | 0.76 | CA2 (0.65) | HPGDSRAB9ANPC1CTDSP1GSK3B | |
| SCHEMBL10346696 | 0.76 | CA2 (0.65) | HPGDSRAB9ANPC1CTDSP1GSK3B | |
| SCHEMBL2714974 | 0.75 | MDM2 (0.43) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL4332252 | 0.75 | LMNA (0.47) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL18803705 | 0.75 | NPC1 (0.59) | HPGDSRAB9ANPC1CTDSP1SMN1; SMN2 | |
| SCHEMBL28917674 | 0.73 | MDM2 (0.44) | ERCC5FEN1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190256454-A1 | NEW PROCESS FOR EARLY SACUBITRIL INTERMEDIATES | NOVARTIS PHARMA AG (CH) | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256454-A1 | NEW PROCESS FOR EARLY SACUBITRIL INTERMEDIATES | MME, ACE, DNPEP | HPGDS 4128/4885ERCC5 3387/4885FEN1 2938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.