SCHEMBL2127486

SCHEMBL2127486

O=C(CS)OC(=S)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.43
TDP1 Q9NUW8 3/20 0.43
MAPK1 P28482 3/20 0.43
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
CYP3A4 P08684 2/20 0.43
HPGD P15428 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4828715 0.98 CES1 (0.42) CES1TDP1MAPK1KMT2AMEN1
SCHEMBL7096723 0.81 TDP1 (0.43) CES1TDP1MAPK1KMT2AMEN1
SCHEMBL28201569 0.80 LMNA (0.52) CES1TDP1MAPK1KMT2AMEN1
SCHEMBL27701934 0.78 LMNA (0.50) CES1TDP1MAPK1KMT2AMEN1
SCHEMBL29234727 0.78 CA2 (0.50) CES1TDP1MAPK1KMT2AMEN1
SCHEMBL489956 0.76 MAPT (0.44) CES1TDP1MAPK1KMT2AMEN1
SCHEMBL27966805 0.75 CES2 (0.53) CES1KMT2AMEN1KDM4EMAPT
SCHEMBL11394434 0.74 ELANE (0.47) CES1TDP1MAPK1KMT2AMEN1
SCHEMBL28399559 0.74 CES1 (0.43) CES1TDP1MAPK1KMT2AMEN1
SCHEMBL1816682 0.74 MAPT (0.50) CES1TDP1MAPK1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3260863-B1 METHOD FOR PERFORMING MULTIPLEX ANALYSIS OF TWO OR MORE ANALYTES FLUIDIGM CANADA INC (CA) 2021-03-10 EP disclosed
US-20200362062-A1 POLYMER BACKBONE ELEMENT TAGS STANDARD BIOTOOLS CANADA INC. (CA) 2020-11-19 US disclosed
US-10752707-B2 Polymer backbone element tags FLUIDIGM CANADA INC. (CA) 2020-08-25 US disclosed
US-10669358-B2 Polymer backbone element tags FLUIDIGM CANADA INC. (CA) 2020-06-02 US disclosed
US-20190345272-A1 POLYMER BACKBONE ELEMENT TAGS STANDARD BIOTOOLS CANADA INC. (CA) 2019-11-14 US disclosed
US-20190077890-A1 POLYMER BACKBONE ELEMENT TAGS FLUIDIGM CANADA INC. (CA) 2019-03-14 US disclosed
US-10072104-B2 Polymer backbone element tags FLUIDIGM CANADA INC. (CA) 2018-09-11 US disclosed
EP-3260863-A1 METHOD FOR PERFORMING MULTIPLEX ANALYSIS OF TWO OR MORE ANALYTES Fluidigm Canada Inc. (CA) 2017-12-27 EP disclosed
EP-2960263-B1 POLYMER BACKBONE ELEMENT TAGS FLUIDIGM CANADA INC (CA) 2017-07-12 EP disclosed
EP-2021793-B1 POLYMER BACKBONE ELEMENT TAGS FLUIDIGM CANADA INC (CA) 2017-04-26 EP disclosed
US-20040082079-A1 Low affinity screening method GRAFFINITY PHARMACEUTICALS AG. (DE) 2004-04-29 US disclosed
EP-1360489-A1 LOW AFFINITY SCREENING METHOD Graffinity Pharmaceuticals Aktiengesellschaft (DE) 2003-11-12 EP disclosed
US-6610837-B1 Preparation of an oligonucleotide compound of given formula by reacting with given compounds, followed by oxidation or sulfurization ISIS PHARMACEUTICALS, INC. 2003-08-26 US disclosed
US-20020127577-A1 Bioactive sensors GRAFFINITY PHARMACEUTICALS AG (DE) 2002-09-12 US disclosed
WO-2002063299-A1 LOW AFFINITY SCREENING METHOD GRAFFINITY PHARMACEUTICALS AG (DE) 2002-08-15 WO disclosed
WO-2000055179-A1 NOVEL PHOSPHATE AND THIOPHOSPHATE PROTECTING GROUPS ISIS PHARMACEUTICALS, INC. (US) 2000-09-21 WO disclosed
US-6121437-A SYNTHESIS OF OLIGONUCLEOTIDES USING OLIGONUCLEOTIDES OR NUCLEOTIDES WITH PROTECTED INTERNUCLEOSIDIC PHOSPHORUS FUNCTIONALITIES WHICH CAN BE REMOVED UNDER MILD CONDITIONS AND PRODUCE NONTOXIC BY-PRODUCTS ISIS PHARMACEUTICALS, INC. (US) 2000-09-19 US disclosed
CN-1094409-A 3 '-thioes derivatives of oxygen-propargyl-trifluorothymidine, it method for making and as the purposes of carcinostatic agent MITSUI TOATSU CHEMICALS (JP) 1994-11-02 CN disclosed
EP-0601520-A1 Trifluorothymidine derivatives, process for producing the same and anti-cancer agent containing the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-06-15 EP disclosed
US-4518682-A CONTAINING COMPOUND WHICH GIVES FOGGING EFFECT FUJI PHOTO FILM CO., LTD. (JP) 1985-05-21 US disclosed