Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.59 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.59 |
| ▸ | PI4KA | P42356 | 1/20 | 0.53 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.53 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326727 | 0.82 | ADORA2A (0.69) | ADORA2AADORA1TMIGD3ADORA2BPI4KA | |
| SCHEMBL18548917 | 0.80 | YTHDC1 (0.62) | ADORA2AADORA1TMIGD3ADORA2BPI4KA | |
| SCHEMBL22326729 | 0.79 | ADORA2A (0.66) | ADORA2AADORA1TMIGD3ADORA2BPI4KA | |
| SCHEMBL5051776 | 0.77 | ADORA2A (0.60) | ADORA2AADORA1TMIGD3ADORA2BPI4KA | |
| SCHEMBL22571186 | 0.76 | TMIGD3 (0.81) | ADORA2AADORA1TMIGD3ADORA2BRAB9A | |
| SCHEMBL23228237 | 0.73 | CYP1A2 (0.72) | ADORA2AADORA1TMIGD3ADORA2BPI4KA | |
| SCHEMBL21943144 | 0.73 | ADORA2A (0.64) | ADORA2AADORA1TMIGD3ADORA2BPI4KA | |
| SCHEMBL12825351 | 0.73 | ADORA2A (0.64) | ADORA2AADORA1TMIGD3ADORA2BPI4KA | |
| SCHEMBL20097160 | 0.72 | CCNB2 (0.69) | ADORA2AADORA1TMIGD3ADORA2BRAB9A | |
| SCHEMBL24196755 | 0.72 | ADORA2A (0.53) | ADORA2AADORA1TMIGD3ADORA2BPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10385090-B2 | Nucleotide derivative or salt thereof, nucleotide-derived 5′-phosphate ester or salt thereof, nucleotide-derived 3′-phosphoramidite compound or salt thereof, and polynucleotide | NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY (JP) | 2019-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385090-B2 | Nucleotide derivative or salt thereof, nucleotide-derived 5′-phosphate ester or salt thereof, nucleotide-derived 3′-phosphoramidite compound or salt thereof, and polynucleotide | SLC34A1, SLC34A2, SLC34A3 | ADORA2A 511/4885ADORA1 132/4885TMIGD3 4335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.