Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.60 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.60 |
| ▸ | PI4KA | P42356 | 1/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326729 | 0.80 | ADORA2A (0.66) | ADORA2AADORA1TMIGD3ADORA2BPI4KA | |
| SCHEMBL22326727 | 0.80 | ADORA2A (0.69) | ADORA2AADORA1TMIGD3ADORA2BPI4KA | |
| SCHEMBL18548917 | 0.77 | YTHDC1 (0.62) | ADORA2AADORA1TMIGD3ADORA2BPI4KA | |
| SCHEMBL21275931 | 0.77 | ADORA2A (0.59) | ADORA2AADORA1TMIGD3ADORA2BPI4KA | |
| SCHEMBL22571186 | 0.77 | TMIGD3 (0.81) | ADORA2AADORA1TMIGD3ADORA2BHTT | |
| SCHEMBL29141662 | 0.76 | ADORA2A (0.63) | ADORA2AADORA1TMIGD3ADORA2BPI4KA | |
| SCHEMBL21078678 | 0.74 | ADORA2A (0.46) | ADORA2AADORA1TMIGD3ADORA2BPI4KA | |
| Acetic Acid SCHEMBL4107415 | 0.72 | ADORA2A (0.82) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL15719749 | 0.71 | PIK3CD (0.53) | ADORA1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27967736 | 0.71 | RAB9A (0.70) | ADORA2AADORA1TMIGD3ADORA2BHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873156-A1 | Process for the preparation of 6-[[(alkoxy)carbonyl]amino]-9H-Purine-9-acetic acid and 4-[(alkoxycarbonyl)amino]-2-oxo-1(2H)-Pyrimidineacetic acid derivatives as synthons for the synthesis of peptide nucleic acids | PerSeptive Biosystems, Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| EP-0840736-A1 | IMPROVED SYNTHONS FOR THE SYNTHESIS AND DEPROTECTION OF PEPTIDE NUCLEIC ACIDS UNDER MILD CONDITIONS | PerSeptive Biosystems, Inc. (US) | 1998-05-13 | — | — | EP | disclosed |
| WO-1996040685-A1 | IMPROVED SYNTHONS FOR THE SYNTHESIS AND DEPROTECTION OF PEPTIDE NUCLEIC ACIDS UNDER MILD CONDITIONS | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0736027-A1 | GUANINE SYNTHONS FOR PEPTIDE NUCLEIC ACID SYNTHESIS AND METHOD FOR PRODUCTION | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017403-A1 | GUANINE SYNTHONS FOR PEPTIDE NUCLEIC ACID SYNTHESIS AND METHOD FOR PRODUCTION | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1995-06-29 | — | — | WO | disclosed |