Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 12/20 | 0.57 |
| ▸ | DCPS | Q96C86 | 7/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30912748 | 1.00 | DHFR (0.57) | DHFRDCPSKCNH2 | |
| SCHEMBL30918024 | 0.84 | ACHE (0.46) | DHFRDCPS | |
| SCHEMBL30482724 | 0.84 | ADORA2A (0.55) | DHFRDCPSKCNH2 | |
| SCHEMBL30482730 | 0.84 | DHFR (0.51) | DHFRDCPSKCNH2 | |
| SCHEMBL13975880 | 0.81 | KCNH2 (0.46) | DHFRDCPSKCNH2 | |
| SCHEMBL21325635 | 0.81 | ALDH1A1 (0.52) | DHFRDCPSKCNH2 | |
| SCHEMBL21497074 | 0.81 | ACHE (0.44) | DHFRDCPSKCNH2 | |
| SCHEMBL2137593 | 0.80 | DCPS (0.65) | DHFRDCPSKCNH2 | |
| SCHEMBL10690347 | 0.79 | DCPS (0.59) | DHFRDCPSKCNH2 | |
| SCHEMBL1154559 | 0.78 | DHFR (0.61) | DHFRDCPSKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118142359-A | Anti-pollution and oxidation-resistant reverse osmosis membrane with low-surface-energy coating and preparation method thereof | 万华化学集团股份有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-110797561-B | Proton exchange membrane based on carbon quantum dots and preparation method thereof | 上海博暄能源科技有限公司 | 2020-10-16 | — | — | CN | claimed |
| CN-111234505-A | Environment-friendly damping rubber plate and preparation method thereof | 谢强 | 2020-06-05 | — | — | CN | claimed |
| CN-110797561-A | Proton exchange membrane based on carbon quantum dots and preparation method thereof | 上海博暄能源科技有限公司 | 2020-02-14 | — | — | CN | claimed |
| CN-118142359-A | Anti-pollution and oxidation-resistant reverse osmosis membrane with low-surface-energy coating and preparation method thereof | 万华化学集团股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-110797561-B | Proton exchange membrane based on carbon quantum dots and preparation method thereof | 上海博暄能源科技有限公司 | 2020-10-16 | — | — | CN | disclosed |
| CN-111234505-A | Environment-friendly damping rubber plate and preparation method thereof | 谢强 | 2020-06-05 | — | — | CN | disclosed |
| CN-111234505-A | Environment-friendly damping rubber plate and preparation method thereof | 谢强 | 2020-06-05 | — | — | CN | disclosed |
| CN-110797561-A | Proton exchange membrane based on carbon quantum dots and preparation method thereof | 上海博暄能源科技有限公司 | 2020-02-14 | — | — | CN | disclosed |
| EP-2709989-B1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES | JANSSEN SCIENCES IRELAND UC (IE) | 2017-12-20 | — | — | EP | disclosed |
| EP-1014953-B1 | FORMULATIONS FOR HYDROPHOBIC PHARMACEUTICAL AGENTS | SUGEN INC (US) | 2012-04-25 | — | — | EP | disclosed |
| CN-100478364-C | Ethylene polymer and molded article obtained therefrom | MITSUI CHEMICALS INC (JP) | 2009-04-15 | — | — | CN | disclosed |
| US-20010014679-A1 | Methods of modulating serine/threonine protein kinase function with quinazoline-based compounds | TANG PENG C (US) | 2001-08-16 | — | — | US | disclosed |
| US-20010012844-A1 | Formulations for hydrophobic pharmaceutical agents | SHENOY NARMADA (US) | 2001-08-09 | — | — | US | disclosed |
| US-6248771-B1 | MIXTURE CONTAINING SURFACTANT; ANTIPROLIFERATIVE AGENTS; KINASE INHIBITOR | SUGEN, INC. | 2001-06-19 | — | — | US | disclosed |
| US-6204267-B1 | Methods of modulating serine/thereonine protein kinase function with quinazoline-based compounds | SUGEN, INC. | 2001-03-20 | — | — | US | disclosed |
| EP-1014953-A2 | FORMULATIONS FOR HYDROPHOBIC PHARMACEUTICAL AGENTS | Sugen, Inc. (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0981519-A1 | METHODS OF MODULATING SERINE/THREONINE PROTEIN KINASE FUNCTION WITH QUINAZOLINE-BASED COMPOUNDS | Sugen, Inc. (US) | 2000-03-01 | — | — | EP | disclosed |
| WO-1998050370-A1 | METHODS OF MODULATING SERINE/THREONINE PROTEIN KINASE FUNCTION WITH QUINAZOLINE-BASED COMPOUNDS | SUGEN, INC. (US) | 1998-11-12 | — | — | WO | disclosed |
| WO-1998038984-A2 | FORMULATIONS FOR HYDROPHOBIC PHARMACEUTICAL AGENTS | SUGEN, INC. (US) | 1998-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010012844-A1 | Formulations for hydrophobic pharmaceutical agents | ABCG2, SLC7A5, SLCO4C1 | DHFR 420/4885DCPS 4329/4885KCNH2 815/4885 |
| US-20010014679-A1 | Methods of modulating serine/threonine protein kinase function with quinazoline-based compounds | RAF1, STK3, MKNK1 | DHFR 1842/4885DCPS 3645/4885KCNH2 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.