Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20558039 | 0.90 | USP2 (0.46) | FAAHUSP2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21276143 | 0.90 | FAAH (0.50) | FAAH | |
| SCHEMBL21276255 | 0.89 | FAAH (0.53) | FAAH | |
| SCHEMBL21276130 | 0.88 | CYP2D6 (0.62) | USP2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21276225 | 0.86 | FAAH (0.46) | FAAHUSP2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21276267 | 0.85 | MGLL (0.49) | — | |
| SCHEMBL21276242 | 0.84 | MGLL (0.49) | FAAH | |
| SCHEMBL17276570 | 0.84 | ALDH1A1 (0.55) | ALDH1A1 | |
| SCHEMBL21276124 | 0.83 | MCHR1 (0.50) | USP2CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL20556855 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10385057-B2 | Pyrazole compounds and methods of making and using same | LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) | 2019-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385057-B2 | Pyrazole compounds and methods of making and using same | FAAH, FAAH2, MGLL | FAAH 1/4885USP2 2128/4885ALDH1A1 1378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.