Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 7/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CCL2 | P13500 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 2/20 | 0.30 |
| ▸ | CDK1 | P06493 | 2/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.30 |
| ▸ | CDK2 | P24941 | 2/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.30 |
| ▸ | PDE2A | O00408 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21281559 | 0.93 | WDR5 (0.32) | WDR5KDM4EPOLBBRD4CCL2 | |
| SCHEMBL21281337 | 0.85 | BRD4 (0.32) | KDM4EPOLBBRD4CCL2 | |
| SCHEMBL23939063 | 0.77 | — | — | |
| SCHEMBL21281357 | 0.74 | CRBN (0.39) | WDR5 | |
| SCHEMBL19310208 | 0.72 | POLB (0.35) | POLB | |
| SCHEMBL23939212 | 0.70 | CRBN (0.39) | KDM4EPOLBAURKACDK1CCNB1 | |
| SCHEMBL21281490 | 0.70 | MAPK14 (0.33) | — | |
| SCHEMBL23939255 | 0.70 | CXCR3 (0.32) | WDR5AURKACDK1CCNB1CDK2 | |
| SCHEMBL21281543 | 0.69 | BDKRB1 (0.34) | WDR5AURKACDK1CCNB1CDK2 | |
| SCHEMBL20459091 | 0.66 | RAB9A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3527210-A1 | COMPOSITION, APPLICATION THEREOF AND TREATMENT METHOD | Kangpu Biopharmaceuticals, Ltd. (CN) | 2019-08-21 | — | — | EP | disclosed |