Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 3/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30301243 | 0.77 | NCF1 (0.59) | NCF1NQO1EGFRAPPNPC1 | |
| SCHEMBL9420844 | 0.77 | NCF1 (0.59) | NCF1NQO1EGFRAPPNPC1 | |
| SCHEMBL21282159 | 0.71 | FYN (0.49) | NCF1NQO1PDGFRADHFRNPC1 | |
| Pyrimidine SCHEMBL11293693 | 0.69 | NCF1 (0.49) | NCF1NQO1EGFRAPPPDGFRA | |
| SCHEMBL13127338 | 0.68 | MAPT (0.65) | NCF1NQO1EGFRAPPPDGFRA | |
| SCHEMBL19965670 | 0.68 | OXTR (0.49) | OXTRPDGFRAPDGFRBALDH1A1 | |
| Hydrochloric Acid SCHEMBL10811605 | 0.67 | PDGFRB (0.54) | NCF1NQO1EGFRAPPHPGDS | |
| SCHEMBL873094 | 0.67 | NCF1 (0.62) | NCF1NQO1EGFRHPGDSNPC1 | |
| SCHEMBL5182975 | 0.66 | OXTR (0.44) | OXTRNPC1RAB9A | |
| SCHEMBL3816388 | 0.65 | NNMT (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190256492-A1 | ALPHA-SYNUCLEIN LIGANDS | WASHINGTON UNIVERSITY (US) | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256492-A1 | ALPHA-SYNUCLEIN LIGANDS | SNCA, PARK7, LRRK2 | OXTR 3886/4885NCF1 1403/4885NQO1 909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.