Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMD1 | P17707 | 5/20 | 0.67 |
| ▸ | HSPA8 | P11142 | 4/20 | 0.66 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | GAPDH | P04406 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | SLC28A2 | O43868 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HBB | P68871 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17406911 | 0.91 | HSPA8 (0.80) | AMD1HSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL15906300 | 0.91 | HSPA8 (0.80) | AMD1HSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL16805420 | 0.91 | HSPA8 (0.80) | AMD1HSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL1135195 | 0.91 | HSPA8 (0.80) | AMD1HSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL18858928 | 0.91 | HSPA8 (0.80) | AMD1HSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL967124 | 0.91 | HSPA8 (0.80) | AMD1HSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL15906323 | 0.91 | HSPA8 (0.80) | AMD1HSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL967122 | 0.91 | HSPA8 (0.80) | AMD1HSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL16378774 | 0.83 | AMD1 (0.77) | AMD1HSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL23548003 | 0.83 | HSPA8 (0.62) | AMD1HSPA8HSPA5RXFP1GAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190255194-A1 | ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNATX INC (US) | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190255194-A1 | ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF | NSUN2, RNGTT, NSUN3 | AMD1 1698/4885HSPA8 1345/4885HSPA5 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.