Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.58 |
| ▸ | RELA | Q04206 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19449707 | 1.00 | MAPT (0.66) | MAPTPOLBLMNAALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL17560885 | 0.98 | MAPT (0.63) | MAPTPOLBLMNAALDH1A1ATM | |
| 2-(1-Phenylethylidene)Hydrazinecarboximidamide SCHEMBL18725202 | 0.84 | LMNA (0.68) | MAPTPOLBLMNAALDH1A1ATM | |
| SCHEMBL16224373 | 0.82 | SMN1; SMN2 (0.48) | MAPTPOLBLMNAALDH1A1METTL3 | |
| SCHEMBL16224314 | 0.80 | MAPT (0.61) | MAPTPOLBLMNAALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL17560956 | 0.80 | SMN1; SMN2 (0.47) | MAPTPOLBLMNAALDH1A1METTL3 | |
| SCHEMBL17574147 | 0.80 | LMNA (0.64) | MAPTPOLBLMNAALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL17560958 | 0.80 | SMN1; SMN2 (0.47) | MAPTPOLBLMNAALDH1A1METTL3 | |
| SCHEMBL7752872 | 0.79 | MAPT (0.78) | MAPTPOLBLMNAALDH1A1ATM | |
| SCHEMBL14938560 | 0.79 | MAPT (0.78) | MAPTPOLBLMNAALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392363-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2019-08-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392363-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | MAPT 3694/4885POLB 3872/4885LMNA 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.