Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3277615 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTGAAKMT2ARAB9A | |
| SCHEMBL24157313 | 0.79 | NFE2L2 (0.42) | ALDH1A1MAPTGAAKMT2ARAB9A | |
| SCHEMBL28906161 | 0.79 | KDM4E (0.46) | ALDH1A1MAPTGAAKMT2ARAB9A | |
| SCHEMBL1482908 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTGAAKMT2ARAB9A | |
| SCHEMBL2556704 | 0.77 | MAPT (0.64) | ALDH1A1MAPTGAAKMT2ARAB9A | |
| SCHEMBL2556700 | 0.77 | MAPT (0.64) | ALDH1A1MAPTGAAKMT2ARAB9A | |
| SCHEMBL27308313 | 0.77 | EGFR (0.60) | MAPTLMNA | |
| SCHEMBL14294535 | 0.74 | CA1 (0.41) | ALDH1A1MAPTGAAKMT2ARAB9A | |
| SCHEMBL11752824 | 0.74 | GFER (0.46) | ALDH1A1MAPTGAAKMT2ARAB9A | |
| SCHEMBL9883332 | 0.74 | CA1 (0.41) | ALDH1A1MAPTGAAKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279677-B2 | Photochromic hydrazone switches | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2022-03-22 | — | — | US | disclosed |
| US-20190256472-A1 | PHOTOCHROMIC HYDRAZONE SWITCHES | DARTMOUTH COLLEGE (US) | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256472-A1 | PHOTOCHROMIC HYDRAZONE SWITCHES | CRYZ, PIN1, PPOX | ALDH1A1 404/4885MAPT 702/4885GAA 4201/4885 |
| US-11279677-B2 | Photochromic hydrazone switches | CRYZ, PIN1, PPOX | ALDH1A1 404/4885MAPT 702/4885GAA 4201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.