SCHEMBL2128447

SCHEMBL2128447

CCCOC(=O)C1C(CO)C1(C)C

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
PPM1B O75688 1/20 0.36
PTPN1 P18031 1/20 0.36
PPP1CC P36873 1/20 0.36
ALDH1A1 P00352 3/20 0.32
HCAR2 Q8TDS4 1/20 0.32
ATM Q13315 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GLA P06280 1/20 0.30
ESR1 P03372 2/20 0.30
CHRM1 P11229 1/20 0.30
TSHR P16473 1/20 0.30
SLC6A2 P23975 1/20 0.30
KDR P35968 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
ESR2 Q92731 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2129276 0.91 ALDH1A1 (0.44) LMNAALDH1A1HCAR2ATMESR1
SCHEMBL2127847 0.89 NAAA (0.43) ALDH1A1HCAR2TSHR
SCHEMBL2128495 0.88 NAAA (0.46) LMNAALDH1A1HCAR2ESR1TSHR
SCHEMBL2128775 0.88 NAAA (0.46) LMNAALDH1A1HCAR2ESR1TSHR
SCHEMBL2129350 0.88 NAAA (0.46) LMNAALDH1A1HCAR2ESR1TSHR
SCHEMBL2128072 0.88 NAAA (0.46) LMNAALDH1A1HCAR2ESR1TSHR
SCHEMBL2127418 0.85 LMNA (0.51) LMNAALDH1A1KDM4ETSHR
SCHEMBL1149828 0.81 ALDH1A1 (0.41) LMNAPPM1BPTPN1PPP1CCALDH1A1
SCHEMBL1685687 0.80 NAAA (0.41) LMNAPPM1BPTPN1PPP1CC
SCHEMBL296125 0.80 LMNA (0.34) LMNAPPM1BPTPN1PPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1535895-B1 PROCESS FOR PRODUCTION OF FORMYLCYCLOPROPANECARBOXYLIC ESTERS SUMITOMO CHEMICAL CO (JP) 2012-04-25 EP disclosed
US-20050240050-A1 Process for production of formylcyclopropanecarboxylic ester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-10-27 US disclosed
EP-1535895-A1 PROCESS FOR PRODUCTION OF FORMYLCYCLOPROPANECARBOXYLIC ESTERS Sumitomo Chemical Company, Limited (JP) 2005-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050240050-A1 Process for production of formylcyclopropanecarboxylic ester AHCYL1, HACL2, CBR1 LMNA 4162/4885PPM1B 4492/4885PTPN1 3760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.