SCHEMBL2128495

SCHEMBL2128495

CCCCCCCCOC(=O)C1C(CO)C1(C)C

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.46
EPHX1 P07099 1/20 0.43
TSHR P16473 3/20 0.42
PPARG P37231 3/20 0.40
GBA2 Q9HCG7 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
RAD52 P43351 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
FAAH O00519 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
ESR1 P03372 1/20 0.39
ACHE P22303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2128775 1.00 NAAA (0.46) NAAAEPHX1TSHRPPARGGBA2
SCHEMBL2128072 1.00 NAAA (0.46) NAAAEPHX1TSHRPPARGGBA2
SCHEMBL2129350 1.00 NAAA (0.46) NAAAEPHX1TSHRPPARGGBA2
SCHEMBL2127847 0.98 NAAA (0.43) NAAAEPHX1TSHRPPARGGBA2
SCHEMBL2129276 0.93 ALDH1A1 (0.44) NAAAEPHX1TSHRPPARGGBA2
SCHEMBL2128447 0.88 LMNA (0.38) TSHRHCAR2ALDH1A1LMNAESR1
SCHEMBL1150513 0.83 ALDH1A1 (0.46) NAAAEPHX1TSHRPPARGHCAR2
SCHEMBL1150187 0.81 ALDH1A1 (0.47) NAAAEPHX1TSHRPPARGHCAR2
SCHEMBL2127418 0.80 LMNA (0.51) TSHRALDH1A1LMNA
SCHEMBL1150644 0.78 LMNA (0.46) NAAAEPHX1TSHRPPARGHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1535895-B1 PROCESS FOR PRODUCTION OF FORMYLCYCLOPROPANECARBOXYLIC ESTERS SUMITOMO CHEMICAL CO (JP) 2012-04-25 EP disclosed
US-20050240050-A1 Process for production of formylcyclopropanecarboxylic ester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-10-27 US disclosed
EP-1535895-A1 PROCESS FOR PRODUCTION OF FORMYLCYCLOPROPANECARBOXYLIC ESTERS Sumitomo Chemical Company, Limited (JP) 2005-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050240050-A1 Process for production of formylcyclopropanecarboxylic ester AHCYL1, HACL2, CBR1 NAAA 306/4885EPHX1 663/4885TSHR 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.