Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | C1S | P09871 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 4/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21285460 | 0.79 | AURKA (0.47) | DGAT1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL21268721 | 0.73 | GPR119 (0.39) | GPR119 | |
| SCHEMBL21268723 | 0.73 | GPR119 (0.39) | GPR119 | |
| SCHEMBL7922940 | 0.70 | GRIA1 (0.41) | MAPTCSF1RCDK4FLT3HRH3 | |
| SCHEMBL21285560 | 0.68 | L3MBTL3 (0.41) | KDM4EMAPTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL21285520 | 0.68 | MAP4K4 (0.38) | MAPTALDH1A1L3MBTL1KDRCCNA2 | |
| SCHEMBL22823018 | 0.68 | MAP4K4 (0.38) | MAPTALDH1A1L3MBTL1KDRCCNA2 | |
| SCHEMBL82007 | 0.67 | L3MBTL3 (0.58) | L3MBTL1HRH3 | |
| SCHEMBL18296369 | 0.64 | L3MBTL3 (0.58) | L3MBTL1HRH3 | |
| SCHEMBL21281590 | 0.64 | PARP1 (0.36) | DGAT1SMN1; SMN2CDK4AURKAINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019158731-A1 | PHARMACEUTICAL 6,5 HETEROBICYCLIC RING DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2019-08-22 | — | — | WO | disclosed |