Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 4/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.32 |
| ▸ | CCND1 | P24385 | 2/20 | 0.32 |
| ▸ | CCND2 | P30279 | 2/20 | 0.32 |
| ▸ | CCND3 | P30281 | 2/20 | 0.32 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.32 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.32 |
| ▸ | NUAK2 | Q9H093 | 1/20 | 0.32 |
| ▸ | MARK1 | Q9P0L2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21285488 | 0.70 | DGAT1 (0.39) | MAPTHRH3FLT3CSF1RCDK4 | |
| SCHEMBL7917230 | 0.69 | CTSL (0.40) | GRIA1GRIA2GRIA3GRIA4FLT3 | |
| SCHEMBL21285460 | 0.64 | AURKA (0.47) | MAPTHRH3CDK4 | |
| SCHEMBL21285560 | 0.64 | L3MBTL3 (0.41) | MAPTHRH3 | |
| SCHEMBL7923029 | 0.63 | PARP1 (0.43) | HRH3 | |
| SCHEMBL7922947 | 0.63 | SORD (0.44) | MAPTHRH3 | |
| SCHEMBL28112415 | 0.61 | CHKA (0.80) | MAPTCHKA | |
| SCHEMBL3612171 | 0.60 | GRM1 (0.48) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7956825 | 0.60 | AKR1C3 (0.54) | MAPTCHKA | |
| SCHEMBL10747566 | 0.60 | KDM4E (0.47) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053127-A1 | MODULATOR OF α1GABAA RECEPTOR OR α5GABAA RECEPTOR | 協和発酵キリン株式会社 (JP) | 2010-05-14 | — | — | WO | disclosed |