Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.50 |
| ▸ | FDPS | P14324 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29828494 | 0.81 | ALDH1A1 (0.58) | MEN1KMT2AHPGDPLA2G1BATG4B | |
| SCHEMBL30805758 | 0.81 | ALDH1A1 (0.58) | MEN1KMT2AHPGDPLA2G1BATG4B | |
| SCHEMBL28420496 | 0.81 | HDAC2 (0.58) | HPGDGGPS1FDPSGLAMAPT | |
| SCHEMBL25990286 | 0.80 | ALOX15 (0.55) | MEN1KMT2AALDH1A1L3MBTL1ATM | |
| SCHEMBL18774007 | 0.78 | KMT2A (0.61) | MEN1KMT2AHPGDPLA2G1BATG4B | |
| SCHEMBL30989309 | 0.78 | TRPV1 (0.61) | MEN1KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL5866871 | 0.76 | ALDH1A1 (0.71) | MEN1KMT2AHPGDPLA2G1BATG4B | |
| SCHEMBL4623293 | 0.76 | ATM (0.44) | MEN1KMT2AHPGDALDH1A1L3MBTL1 | |
| SCHEMBL28427493 | 0.75 | SMN1; SMN2 (0.48) | HPGDGGPS1FDPSALDH1A1SMN1; SMN2 | |
| SCHEMBL21233937 | 0.75 | MEN1 (0.65) | MEN1KMT2AHPGDPLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101271-A1 | DIAMINE SYNTHESIS VIA CATALYTIC C-H AMINATION OF AZIDES | NATIONAL SCIENCE FOUNDATION | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101271-A1 | DIAMINE SYNTHESIS VIA CATALYTIC C-H AMINATION OF AZIDES | DOHH, AOC1, ESD | MEN1 2425/4885KMT2A 262/4885HPGD 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.