Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21290220 | 0.85 | PDCD1 (0.35) | — | |
| SCHEMBL21289799 | 0.83 | KDM4E (0.34) | TGFBR1 | |
| SCHEMBL24291650 | 0.82 | — | — | |
| SCHEMBL25100533 | 0.82 | — | — | |
| SCHEMBL21290205 | 0.80 | LDHA (0.31) | — | |
| SCHEMBL21125469 | 0.80 | ENPP3 (0.35) | TGFBR1 | |
| SCHEMBL21125944 | 0.79 | HSD17B1 (0.36) | TGFBR1 | |
| SCHEMBL18015374 | 0.78 | ADORA1 (0.36) | TGFBR1 | |
| SCHEMBL22059833 | 0.77 | TGFBR1 (0.35) | TGFBR1 | |
| SCHEMBL19933714 | 0.77 | TGFBR1 (0.33) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752512-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| WO-2019158453-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-08-22 | — | — | WO | disclosed |