SCHEMBL21291475

SCHEMBL21291475

FC(F)(F)c1ccccc1-c1cccc(-c2nc(-c3cccc(-c4ccccc4C(F)(F)F)c3)nc(-c3cccc(-c4ccccc4C(F)(F)F)c3)n2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 7/20 0.59
TRPA1 O75762 4/20 0.51
BACE1 P56817 1/20 0.51
TRPM8 Q7Z2W7 1/20 0.51
AR P10275 1/20 0.49
SCN10A Q9Y5Y9 1/20 0.47
DPP4 P27487 1/20 0.47
GRM5 P41594 1/20 0.46
PIK3R1 P27986 1/20 0.46
PIK3CA P42336 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
HIF1A Q16665 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HSD11B1 P28845 1/20 0.44
NR3C1 P04150 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26369951 0.91 SCN9A (0.51) SCN9ATRPA1BACE1TRPM8AR
SCHEMBL28899688 0.83 SCN9A (0.57) SCN9ATRPA1BACE1TRPM8AR
SCHEMBL30146607 0.83 SCN9A (0.59) SCN9ATRPA1BACE1TRPM8AR
SCHEMBL4484659 0.81 TRPA1 (0.52) SCN9ATRPA1BACE1TRPM8CYP1A2
SCHEMBL4559050 0.80 SCN9A (0.56) SCN9ATRPA1BACE1TRPM8AR
SCHEMBL17263699 0.79 L3MBTL1 (0.44) SCN9ATRPA1ALOX15TSHR
SCHEMBL17263740 0.78 L3MBTL1 (0.43) SCN9ATRPA1ALOX15TSHR
SCHEMBL5112656 0.78 SCN9A (0.54) SCN9ATRPA1BACE1TRPM8AR
SCHEMBL20022130 0.77 SCN9A (0.54) SCN9ATRPA1BACE1TRPM8AR
SCHEMBL20022145 0.77 SCN9A (0.54) SCN9ATRPA1BACE1TRPM8AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11778908-B2 Organic electroluminescent devices KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD. (CN) 2023-10-03 US disclosed
US-11063224-B2 Organic electroluminescent device KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD. (CN) 2021-07-13 US disclosed
US-20200203610-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND PREPARATION METHOD AND DISPLAY APPARATUS THEREOF KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2020-06-25 US disclosed
US-20190259959-A1 ORGANIC ELECTROLUMINESCENT DEVICE KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD. (CN) 2019-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11778908-B2 Organic electroluminescent devices LAGE3, ELAVL3, ILK SCN9A 2041/4885TRPA1 379/4885BACE1 3623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.