Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2130085 | 0.88 | MTNR1B (0.54) | KDM4ENPC1RAB9AGAAGFER | |
| SCHEMBL2127101 | 0.81 | RAB9A (0.51) | KDM4EMAPTNPC1RAB9AGAA | |
| SCHEMBL2127814 | 0.76 | NPC1 (0.57) | KDM4EMAPTNPC1RAB9AGAA | |
| SCHEMBL6228012 | 0.73 | SLC6A3 (0.47) | KDM4EMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL24419014 | 0.71 | KMT2A (0.52) | KDM4EMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3393116 | 0.71 | MTNR1B (0.41) | KDM4ENPC1RAB9AGAAGFER | |
| SCHEMBL6526380 | 0.69 | MAPT (0.63) | KDM4EMAPTNPC1RAB9AGAA | |
| SCHEMBL3499455 | 0.68 | SLC2A1 (0.52) | KDM4EMAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL2127536 | 0.68 | AKT1 (0.58) | KDM4EMAPTNPC1RAB9AGAA | |
| SCHEMBL2128509 | 0.68 | ALDH1A1 (0.64) | KDM4EMAPTNPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129375-B1 | IMIDAZO[1,2-A]PYRIDINES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2012-04-25 | — | — | EP | claimed |