Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | AKT2 | P31751 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 3/20 | 0.45 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500174 | 0.89 | SLC2A1 (0.50) | SLC2A1BRD4DHODHCYP1A2CYP2C9 | |
| SCHEMBL2127101 | 0.88 | RAB9A (0.51) | BRD4AKT1AKT2KDM4EALDH1A1 | |
| SCHEMBL2127536 | 0.87 | AKT1 (0.58) | BRD4CYP1A2CYP2C9CYP2C19AKT1 | |
| SCHEMBL3498796 | 0.86 | CYP1A2 (0.49) | SLC2A1BRD4DHODHCYP1A2CYP2C9 | |
| SCHEMBL1691320 | 0.84 | SLC2A1 (0.56) | SLC2A1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| Bromide SCHEMBL1691362 | 0.83 | SLC2A1 (0.56) | SLC2A1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL26931747 | 0.79 | BRD4 (0.51) | BRD4AKT1AKT2LMNAKDM4E | |
| SCHEMBL5340340 | 0.77 | SLC2A1 (0.64) | SLC2A1CYP1A2CYP2C9CYP2C19AKT1 | |
| SCHEMBL5352452 | 0.76 | SLC2A1 (0.63) | SLC2A1CYP1A2CYP2C9CYP2C19AKT1 | |
| SCHEMBL14646314 | 0.76 | GABRA1 (0.53) | SLC2A1BRD4AKT1AKT2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | SLC2A1 1193/4885BRD4 393/4885DHODH 3981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.