Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3850930 | 0.85 | KDM4E (0.75) | KDM4EKMT2AALDH1A1TSHRMEN1 | |
| SCHEMBL7811485 | 0.83 | KDM4E (0.67) | KDM4EKMT2AALDH1A1TSHRMEN1 | |
| SCHEMBL3482945 | 0.79 | KDM4E (0.62) | KDM4EKMT2AALDH1A1TSHRMEN1 | |
| SCHEMBL7712450 | 0.78 | KDM4E (0.61) | KDM4EKMT2AALDH1A1TSHRMEN1 | |
| SCHEMBL7687272 | 0.78 | KDM4E (0.61) | KDM4EKMT2AALDH1A1TSHRMEN1 | |
| SCHEMBL1922261 | 0.78 | KDM4E (0.61) | KDM4EKMT2AALDH1A1TSHRMEN1 | |
| SCHEMBL1420044 | 0.78 | KDM4E (0.61) | KDM4EKMT2AALDH1A1TSHRMEN1 | |
| SCHEMBL7706563 | 0.78 | KDM4E (0.61) | KDM4EKMT2AALDH1A1TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL1894628 | 0.78 | KDM4E (0.60) | KDM4EKMT2AALDH1A1TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL1784781 | 0.78 | KDM4E (0.60) | KDM4EKMT2AALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3759075-B1 | COMPOUNDS WITH FERROPTOSIS INDUCING ACTIVITY AND METHODS OF THEIR USE | FERRO THERAPEUTICS INC (US) | 2025-07-23 | — | — | EP | disclosed |
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | FERRO THERAPEUTICS INC (US) | 2023-02-09 | — | — | US | disclosed |
| US-20190263802-A1 | COMPOUNDS AND METHOD OF USE | MOLECULAR SKIN THERAPEUTICS, INC. | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | KDM4E 2312/4885KMT2A 2510/4885ALDH1A1 1254/4885 |
| US-20190263802-A1 | COMPOUNDS AND METHOD OF USE | AIFM2, GPX4, GPX1 | KDM4E 2426/4885KMT2A 2475/4885ALDH1A1 1190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.