Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.60 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.60 |
| ▸ | NPY1R | P25929 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL18340778 | 1.00 | SIRT6 (0.60) | SIRT6SIRT1NPY1RCA1CA2 | |
| SCHEMBL19681219 | 0.84 | SIRT6 (0.72) | SIRT6SIRT1CA1CA2SIRT5 | |
| SCHEMBL21293944 | 0.82 | SIRT1 (0.56) | SIRT6SIRT1NPY1RCA1CA2 | |
| SCHEMBL21309617 | 0.79 | SIRT6 (0.69) | SIRT6SIRT1CA1CA2SIRT5 | |
| SCHEMBL19384798 | 0.78 | CA1 (0.63) | SIRT6SIRT1CA1CA2GRIA1 | |
| SCHEMBL19401687 | 0.78 | CA1 (0.63) | SIRT6SIRT1CA1CA2GRIA1 | |
| SCHEMBL21167105 | 0.77 | SIRT6 (0.62) | SIRT6SIRT1NPY1RCA1CA2 | |
| Trifluoroacetic Acid SCHEMBL30587887 | 0.76 | TLR2 (0.53) | SIRT6SIRT1NPY1RCA1CA2 | |
| SCHEMBL23610946 | 0.74 | SIRT1 (0.57) | SIRT6SIRT1CA1CA2TLR2 | |
| SCHEMBL15359505 | 0.74 | SIRT6 (0.54) | SIRT6SIRT1CA1CA2SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190262463-A1 | SITE SPECIFIC HOMOGENEOUS WITH KSP INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190262463-A1 | SITE SPECIFIC HOMOGENEOUS WITH KSP INHIBITORS | KIF5B, KIF15, KIF2C | SIRT6 2866/4885SIRT1 3442/4885NPY1R 4782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.