Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6383954 | 0.78 | USP2 (0.43) | ALDH1A1POLBESR1KDM4EHSD17B10 | |
| SCHEMBL18365961 | 0.70 | RIPK1 (0.47) | SPRRIPK1 | |
| SCHEMBL23535256 | 0.68 | CYP4F2 (0.35) | POLBESR1KDM4E | |
| SCHEMBL21295175 | 0.68 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL1423651 | 0.67 | HTR2A (0.44) | — | |
| SCHEMBL26526759 | 0.67 | MPO (0.34) | — | |
| SCHEMBL3310783 | 0.65 | HDAC6 (0.41) | ALDH1A1POLBRIPK1 | |
| SCHEMBL25412001 | 0.65 | GRM5 (0.46) | — | |
| SCHEMBL12282789 | 0.65 | PDCD1 (0.43) | POLBTSHRHCAR2 | |
| SCHEMBL1815818 | 0.65 | KMO (0.42) | ALDH1A1POLBRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3755700-B1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER AG (DE) | 2021-11-24 | — | — | EP | disclosed |
| US-11019821-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-06-01 | — | — | US | disclosed |
| US-11019821-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3755700-A1 | CONDENSED BICYCLIC HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | Bayer Aktiengesellschaft (DE) | 2020-12-30 | — | — | EP | disclosed |
| US-20200383334-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-12-10 | — | — | US | disclosed |
| US-20200383334-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-12-10 | — | — | US | disclosed |
| CN-111741958-A | Fused bicyclic heterocyclic derivatives as pest control agents | 拜耳公司 | 2020-10-02 | — | — | CN | disclosed |
| WO-2019162174-A1 | CONDENSED BICYCLIC HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-08-29 | — | — | WO | disclosed |
| WO-2019162174-A1 | CONDENSED BICYCLIC HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11019821-B2 | Fused bicyclic heterocycle derivatives as pesticides | DDT, BCHE, ACHE | ALDH1A1 299/4885POLB 3922/4885ESR1 3436/4885 |
| US-20200383334-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, BCHE, ACHE | ALDH1A1 299/4885POLB 3922/4885ESR1 3436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.