SCHEMBL21295175

SCHEMBL21295175

O=C(O)c1nn2c(c1Br)CC(C(F)(F)F)CC2

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21315389 0.81 POLB (0.36) RIPK1
SCHEMBL18365961 0.77 RIPK1 (0.47) RIPK1
SCHEMBL28480405 0.69
SCHEMBL28643148 0.68 KMT2A (0.32)
SCHEMBL22888198 0.68 RIPK1 (0.46) RIPK1
SCHEMBL21295147 0.68 ALDH1A1 (0.36) RIPK1
SCHEMBL18366528 0.67 RIPK1 (0.48) RIPK1
SCHEMBL28413022 0.65 RIPK1 (0.48) RIPK1
SCHEMBL18366109 0.64 RIPK1 (0.50) RIPK1
SCHEMBL19659082 0.64 RIPK1 (0.50) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3755700-B1 CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AG (DE) 2021-11-24 EP disclosed
US-11019821-B2 Fused bicyclic heterocycle derivatives as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2021-06-01 US disclosed
US-11019821-B2 Fused bicyclic heterocycle derivatives as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2021-06-01 US disclosed
EP-3755700-A1 CONDENSED BICYCLIC HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS Bayer Aktiengesellschaft (DE) 2020-12-30 EP disclosed
US-20200383334-A1 FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2020-12-10 US disclosed
US-20200383334-A1 FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2020-12-10 US disclosed
CN-111741958-A Fused bicyclic heterocyclic derivatives as pest control agents 拜耳公司 2020-10-02 CN disclosed
WO-2019162174-A1 CONDENSED BICYCLIC HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2019-08-29 WO disclosed
WO-2019162174-A1 CONDENSED BICYCLIC HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2019-08-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11019821-B2 Fused bicyclic heterocycle derivatives as pesticides DDT, BCHE, ACHE RIPK1 4393/4885
US-20200383334-A1 FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES DDT, BCHE, ACHE RIPK1 4393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.