SCHEMBL21296037

SCHEMBL21296037

[c]1oc2ccccc2c1-c1ccncc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.40
MAPK14 Q16539 1/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
ATAD2 Q6PL18 1/20 0.36
HSD17B10 Q99714 3/20 0.36
IMPDH2 P12268 2/20 0.36
MAPK1 P28482 2/20 0.36
MAPT P10636 5/20 0.36
LMNA P02545 4/20 0.36
HIF1A Q16665 1/20 0.36
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.34
KDM4E B2RXH2 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
HTT P42858 1/20 0.33
CYP17A1 P05093 1/20 0.33
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2958656 0.84 CA1 (0.36) NPC1RAB9AHSD17B10MAPK1MAPT
SCHEMBL21295803 0.81 ALDH1A1 (0.45) NPC1RAB9AHSD17B10MAPTLMNA
SCHEMBL4455299 0.78 GABRP (0.42) MAPK14MAPTALDH1A1SMN1; SMN2
SCHEMBL5567669 0.76 KDM4E (0.36) NPC1RAB9AHSD17B10MAPTLMNA
SCHEMBL15673590 0.75 CYP2A6 (0.42) MEN1KMT2ACYP3A4CYP2C9CYP2C19
SCHEMBL646759 0.73 KDM4E (0.45) NPC1RAB9AHSD17B10MAPK1MAPT
SCHEMBL6430073 0.73 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL5984762 0.72 IKBKE (0.44) NPC1RAB9AHSD17B10MAPK1MAPT
SCHEMBL5324075 0.70 NPC1 (0.50) NPC1RAB9AHSD17B10MAPK1MAPT
SCHEMBL3028469 0.70 BRD4 (0.40) HSD17B10MAPTALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed