Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430073 | 0.85 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL646759 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL21296037 | 0.76 | NOTUM (0.40) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL3028469 | 0.75 | BRD4 (0.40) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL7808907 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL3685297 | 0.74 | ADRA2A (0.45) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2958656 | 0.74 | CA1 (0.36) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL21295803 | 0.72 | ALDH1A1 (0.45) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL18957373 | 0.72 | DHODH (0.34) | — | |
| SCHEMBL4960655 | 0.69 | ADORA3 (0.43) | KDM4EALDH1A1MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11072573-B2 | Binaphthyl compounds | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2021-07-27 | — | — | US | disclosed |
| US-20200354299-A1 | BINAPHTHYL COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2020-11-12 | — | — | US | disclosed |
| EP-3676239-A1 | BINAPHTHYL COMPOUNDS | Reuter Chemische Apparatenbau e.K. (DE) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019043060-A1 | BINAPHTHYL COMPOUNDS | REUTER CHEMISCHE APPARATEBAU KG (DE) | 2019-03-07 | — | — | WO | disclosed |
| EP-1758911-A1 | 1-HETEROCYCLYL-1,5-DIHYDRO-PYRIDO[3,2-B]INDOL-2-ONES | Tibotec Pharmaceuticals Ltd. (IE) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005111047-A1 | 1-HETEROCYCLYL-1,5-DIHYDRO-PYRIDO[3,2-B]INDOL-2-ONES | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354299-A1 | BINAPHTHYL COMPOUNDS | UACA, C9, C1S | KDM4E 1333/4885ALDH1A1 1476/4885MAPT 4050/4885 |
| US-11072573-B2 | Binaphthyl compounds | UACA, C9, C1S | KDM4E 1333/4885ALDH1A1 1476/4885MAPT 4050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.