SCHEMBL21296563

SCHEMBL21296563

CC(P)c1cccc(C(C)P)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HDAC4 P56524 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
MDM4 O15151 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
TYR P14679 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
CA5A P35218 1/20 0.37
HTT P42858 1/20 0.37
MDM2 Q00987 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA9 Q16790 1/20 0.37
HDAC2 Q92769 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8470837 0.85 ACHE (0.50) ALDH1A1TP53HPGDTDP1TAAR1
SCHEMBL941382 0.79
SCHEMBL19171565 0.78 ACHE (0.46) KDM4EALDH1A1HTTSMN1; SMN2
Hydrochloric Acid SCHEMBL9619438 0.77 TDP1 (0.48) KDM4EALDH1A1MAPTTDP1HTR2A
Bromide SCHEMBL4970617 0.77 NOS2 (0.46) KDM4EALDH1A1TDP1HTR2ATAAR1
Iodide SCHEMBL10775392 0.77 KDM4E (0.44) KDM4EALDH1A1TDP1HTR2ATAAR1
SCHEMBL374780 0.75 HDAC4 (0.56) KDM4EALDH1A1HDAC4HDAC8MDM4
Hydrochloric Acid SCHEMBL28208708 0.74 CYP2D6 (0.46) KDM4EALDH1A1MAPTTDP1HTR2A
Hydrochloric Acid SCHEMBL28254127 0.74 TDP1 (0.46) KDM4EALDH1A1MAPTTDP1HTR2A
Water SCHEMBL9322811 0.73 HDAC4 (0.54) KDM4EALDH1A1HDAC4HDAC8MDM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399195-A1 SELECTIVE 1-HEXENE/1-OCTENE PRODUCTION WITH 1-DECENE Chevron Phillips Chemical Company LP (US) 2024-07-17 EP disclosed
CN-117916214-A Selective production of 1-hexene/1-octene with 1-decene 切弗朗菲利浦化学公司 2024-04-19 CN disclosed
WO-2023038848-A1 SELECTIVE 1-HEXENE/1-OCTENE PRODUCTION WITH 1-DECENE CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-03-16 WO disclosed
US-11072569-B2 Normal alpha olefin synthesis using dehydroformylation or dehydroxymethylation CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2021-07-27 US disclosed
EP-3759063-A1 NORMAL ALPHA OLEFIN SYNTHESIS USING DEHYDROFORMYLATION OR DEHYDROXYMETHYLATION Bischof, Steven M. (US) 2021-01-06 EP disclosed
US-20200331823-A1 Normal Alpha Olefin Synthesis Using Dehydroformylation or Dehydroxymethylation CHEVRON PHILLIPS CHEMICAL COMPANY LP 2020-10-22 US disclosed
WO-2019165350-A1 NORMAL ALPHA OLEFIN SYNTHESIS USING DEHYDROFORMYLATION OR DEHYDROXYMETHYLATION BISCHOF STEVEN M (US) 2019-08-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200331823-A1 Normal Alpha Olefin Synthesis Using Dehydroformylation or Dehydroxymethylation ADH1A, ADH1C, DHPS KDM4E 3894/4885ALDH1A1 22/4885HDAC4 4041/4885
US-11072569-B2 Normal alpha olefin synthesis using dehydroformylation or dehydroxymethylation ADH1A, ADH1C, DHPS KDM4E 3894/4885ALDH1A1 22/4885HDAC4 4041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.