SCHEMBL21298046

SCHEMBL21298046

c1ccc2cc3c(cc2c1)c1cc2ccccc2cc1n1c2ccccc2cc31

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.36
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 3/20 0.36
HIF1A Q16665 1/20 0.36
CYP1B1 Q16678 1/20 0.36
NQO1 P15559 1/20 0.35
KMT2A Q03164 3/20 0.35
HTR2A P28223 2/20 0.35
HTR2C P28335 2/20 0.35
ENPP3 O14638 1/20 0.35
LMNA P02545 2/20 0.34
DAO P14920 2/20 0.34
KDM4E B2RXH2 2/20 0.34
TERT O14746 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
CASP1 P29466 1/20 0.33
GALK1 P51570 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18069003 0.94 ENPP3 (0.38) CDC25BALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL21298364 0.84 MEN1 (0.40) ALDH1A1KMT2AENPP3KDM4EMEN1
SCHEMBL31116733 0.82 ENPP3 (0.41) CDC25BALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL16050180 0.82 ENPP3 (0.41) CDC25BALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL21298500 0.82 ALDH1A1 (0.39) CDC25BALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL21298152 0.82 ALDH1A1 (0.39) CDC25BALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL21298150 0.82 HSD17B10 (0.39) CDC25BALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL21298153 0.82 MAPK1 (0.40) ALDH1A1HSD17B10KMT2AENPP3LMNA
SCHEMBL21790854 0.81 HSD17B10 (0.38) CDC25BALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL31116732 0.81 HPRT1 (0.43) CDC25BALDH1A1HSD17B10KMT2AENPP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2021-01-28 US disclosed
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2020-03-05 US disclosed
US-10392387-B2 Substituted benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,8]naphthyridines, benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,5]naphthyridines and dibenzo[f,h]benzo[4,5]imidazo[2,1-a]pyrazino[2,3-c]isoquinolines as thermally assisted delayed fluorescent materials ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2019-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS CDC25B 1997/4885ALDH1A1 2839/4885HSD17B10 3931/4885
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS CDC25B 1997/4885ALDH1A1 2839/4885HSD17B10 3931/4885
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS CDC25B 1997/4885ALDH1A1 2839/4885HSD17B10 3931/4885
US-10392387-B2 Substituted benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,8]naphthyridines, benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,5]naphthyridines and dibenzo[f,h]benzo[4,5]imidazo[2,1-a]pyrazino[2,3-c]isoquinolines as thermally assisted delayed fluorescent materials NT5C, HTR3D, IK CDC25B 2524/4885ALDH1A1 326/4885HSD17B10 3563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.