Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2380417 | 0.81 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL17803853 | 0.79 | TP53 (0.40) | ALDH1A1SMN1; SMN2TP53LMNATPSAB1 | |
| SCHEMBL23519429 | 0.76 | TP53 (0.37) | ALDH1A1SMN1; SMN2TP53LMNA | |
| SCHEMBL29603305 | 0.75 | TP53 (0.37) | ALDH1A1SMN1; SMN2TP53LMNA | |
| SCHEMBL16384737 | 0.73 | TPSAB1 (0.49) | ALDH1A1MEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL23879899 | 0.73 | KMT2A (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL26036197 | 0.73 | TPSAB1 (0.49) | ALDH1A1MEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL21422726 | 0.73 | TPSAB1 (0.46) | ALDH1A1MEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL15326722 | 0.73 | TP53 (0.42) | ALDH1A1SMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL21301043 | 0.72 | MEN1 (0.48) | ALDH1A1MEN1KMT2AMAPTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361098-B1 | COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET | MASSACHUSETTS GEN HOSPITAL (US) | 2019-08-28 | — | — | EP | disclosed |