Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21301042 | 0.86 | KMO (0.43) | KMOTRPV4POLBMAPT | |
| SCHEMBL21301067 | 0.78 | HDAC4 (0.37) | KMOTRPV4MEN1KMT2AACHE | |
| SCHEMBL21300934 | 0.77 | KMO (0.40) | KMOTRPV4ACHE | |
| SCHEMBL21300927 | 0.76 | MAPK1 (0.44) | KMOSAE1POLBMEN1KMT2A | |
| SCHEMBL21300945 | 0.74 | KMO (0.49) | KMOTRPV4ACHEALDH1A1MAPT | |
| SCHEMBL23791842 | 0.74 | FBP1 (0.43) | KMOPOLBMEN1KMT2APTGDR2 | |
| SCHEMBL21301065 | 0.72 | KMO (0.41) | KMOTRPV4MEN1KMT2AACHE | |
| SCHEMBL21301171 | 0.69 | KMO (0.40) | KMOTRPV4MEN1KMT2AACHE | |
| SCHEMBL21301089 | 0.68 | ACHE (0.42) | KMOTRPV4ACHEHTR7HTR2C | |
| SCHEMBL17407219 | 0.67 | HTT (0.35) | KMOTRPV4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2963036-B1 | 2-ACYLAMINOTHIAZOLE DERIVATIVE AND SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2019-08-28 | — | — | EP | disclosed |